SCHEMBL794226

SCHEMBL794226

CN(C)CCCNC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.53
KDM4E B2RXH2 5/20 0.49
PAOX Q6QHF9 1/20 0.47
HPGD P15428 1/20 0.46
HTT P42858 2/20 0.44
TSHR P16473 1/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
P2RX4 Q99571 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL793323 0.98 DNM1 (0.52) DNM1KDM4EPAOXHPGDHTT
Methylamine SCHEMBL28500749 0.96 DNM1 (0.50) DNM1KDM4EPAOXHPGDHTT
SCHEMBL20501368 0.93 KDM4E (0.49) DNM1KDM4EPAOXTSHRALDH1A1
SCHEMBL27503353 0.88 DNM1 (0.53) DNM1KDM4EPAOXHPGDHTT
SCHEMBL1414877 0.85
SCHEMBL18339127 0.84 SIGMAR1 (0.41) DNM1
Hydrochloric Acid SCHEMBL17022764 0.83 DNM1 (0.47) DNM1KDM4EHTTALDH1A1
SCHEMBL78355 0.83 KDM4E (0.59) DNM1KDM4EPAOXHPGDHTT
SCHEMBL36169 0.83 DNM1 (0.55) DNM1KDM4EPAOXHPGDHTT
SCHEMBL9702900 0.82 KDM4E (0.54) DNM1KDM4EPAOXHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773121-B2 Antiviral compounds VIROVAX LLC (US) 2023-10-03 US claimed
US-20210238210-A1 ANTIVIRAL COMPOUNDS VIROVAX LLC 2021-08-05 US claimed
EP-3609888-A1 FARNESOID X RECEPTOR AGONISTS AND USES THEREOF Metacrine, Inc. (US) 2020-02-19 EP claimed
US-10470465-B2 Glomus iranicum var. tenuihypharum var. nov. strain and use thereof as biostimulant SYMBORG, S.L. (ES) 2019-11-12 US claimed
WO-2018170182-A1 FARNESOID X RECEPTOR AGONISTS AND USES THEREOF METACRINE, INC. (US) 2018-09-20 WO claimed
EP-2667718-B1 COMPOSITION COMPRISING AN ELICITOR OF THE PLANT IMMUNE SYSTEM FYTOFEND S A (BE) 2016-03-30 EP claimed
CN-102498095-A Indoline derivatives TOKYO INST TECH 2012-06-13 CN claimed
US-8173653-B2 Pyridiazinone derivatives for the treatment of tumours MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-05-08 US claimed
EP-1960370-B1 PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT MERCK PATENT GMBH (DE) 2011-10-05 EP claimed
US-20080293719-A1 Pyridiazinone Derivatives for the Treatment of Tumours MERCK PATENT GESELLSCHAFT (DE) 2008-11-27 US claimed
CN-1191257-C Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them SERVIER LAB (FR) 2005-03-02 CN claimed
EP-0874809-B1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-08-27 EP claimed
CN-1437604-A Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-08-20 CN claimed
EP-0946093-B1 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO SPA (IT) 2002-08-28 EP claimed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US claimed
US-5480989-A Carbamates of rapamycin AMERICAN HOME PRODUCTS CORPORATION (US) 1996-01-02 US claimed
US-5227401-A ETHYNYL ALANINE AMINO DIOL COMPOUNDS FOR TREATMENT OF HYPERTENSION G. D. SEARLE & CO. (US) 1993-07-13 US claimed
EP-0280348-B1 FUNGICIDAL COMPOSITIONS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-09-23 EP claimed
US-4400312-A WATER, A HYDROXIDE, AND A DIALKYLAMINO DITHIO CARBAMIC ACID, A MERCAPTO ALKANONE, OR A 3-HYDROXYTHIETANE PHILLIPS PETROLEUM COMPANY (US) 1983-08-23 US claimed
US-11945806-B2 Stabilization of amyloidogenic immunoglobulin light chains THE SCRIPPS RESEARCH INSTITUTE 2024-04-02 US disclosed
EP-3509418-B1 SEED COATINGS COMPRISING PESTICIDE TERRAMERA EXCO HOLDINGS LTD (CA) 2023-11-15 EP disclosed
WO-2023154818-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2023-08-17 WO disclosed
WO-2023076605-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed
US-20230109183-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF ARBUTUS BIOPHARMA CORPORATION (US) 2023-04-06 US disclosed
US-20220204485-A1 STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS THE SCRIPPS RESEARCH INSTITUTE 2022-06-30 US disclosed
EP-3988104-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF Arbutus Biopharma Corporation (CA) 2022-04-27 EP disclosed
EP-3950692-A1 NOVEL TRICYCLIC COMPOUNDS AbbVie Inc. (US) 2022-02-09 EP disclosed
EP-3946604-A1 BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS The Scripps Research Institute (US) 2022-02-09 EP disclosed
US-11236071-B1 Farnesoid X receptor agonists and uses thereof METACRINE, INC. (US) 2022-02-01 US disclosed
EP-3473611-B1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF ARBUTUS BIOPHARMA CORP (CA) 2021-10-20 EP disclosed
CN-109053742-B Novel tricyclic compounds ABBVIE 公司 2021-06-15 CN disclosed
US-20210061813-A1 NOVEL TRICYCLIC COMPOUNDS ABBVIE INC. (US) 2021-03-04 US disclosed
EP-3774722-A1 OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO Epiodyne, Inc. (US) 2021-02-17 EP disclosed
WO-2020205683-A1 BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS THE SCRIPPS RESEARCH INSTITUTE (US) 2020-10-08 WO disclosed
US-20200306378-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF ARBUTUS BIOPHARMA CORPORATION (CA) 2020-10-01 US disclosed
EP-3677567-A1 COMPOSITIONS AND METHODS FOR DELIVERING MESSENGER RNA Arbutus Biopharma Corporation (CA) 2020-07-08 EP disclosed
US-10561732-B2 Trialkyl cationic lipids and methods of use thereof ARBUTUS BIOPHARMA CORPORATION (CA) 2020-02-18 US disclosed
WO-2019195634-A1 OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO EPIODYNE, INC. (US) 2019-10-10 WO disclosed
US-20190254285-A1 SODIUM PHOSPHITE COMBINATIONS CERADIS PATENT B.V. (NL) 2019-08-22 US disclosed
EP-3509418-A1 SEED COATINGS COMPRISING PESTICIDE Exosect Limited (GB) 2019-07-17 EP disclosed
EP-3503732-A1 SODIUM PHOSPHITE COMBINATIONS Arec Crop Protection B.V. (NL) 2019-07-03 EP disclosed
EP-3233790-B1 CHEMICAL BLOWING AGENT AND THERMALLY EXPANDABLE THERMOPLASTIC COMPOSITION SIKA TECH AG (CH) 2019-06-26 EP disclosed
CN-109673655-A The bactericidal composition of the amine of bacterium containing figured silk fabrics and its application 陕西标正作物科学有限公司 2019-04-26 CN disclosed
US-RE47221-E1 Tricyclic compounds ABBVIE INC. (US) 2019-02-05 US disclosed
EP-2817287-B1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF ARBUTUS BIOPHARMA CORP (CA) 2018-10-03 EP disclosed
WO-2018149816-A1 COMPOSITIONS FOR APPLICATION TO AERIAL PARTS OF PLANTS EXOSECT LIMITED (GB) 2018-08-23 WO disclosed
WO-2018044161-A1 SODIUM PHOSPHITE COMBINATIONS AREC CROP PROTECTION B.V. (NL) 2018-03-08 WO disclosed
CN-105165883-B Fungicidal mixture based on azoles and pyrimidine radicals amine 巴斯夫欧洲公司 2018-01-30 CN disclosed
EP-3266786-A1 NOVEL TRICYCLIC COMPOUNDS AbbVie Inc. (US) 2018-01-10 EP disclosed
WO-2017216193-A1 SEED COATINGS COMPRISING PESTICIDE EXOSECT LIMITED (GB) 2017-12-21 WO disclosed
CN-107075712-A Non-amphoteric, quaternizable and water-soluble polymers for modifying the surface charge of solid particles 巴斯夫欧洲公司 2017-08-18 CN disclosed
US-20170204076-A1 SYNTHESIS AND USE OF AMINO LIPIDS SCREENFECT GMBH (DE) 2017-07-20 US disclosed
US-20170007702-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF PROTIVA BIOTHERAPEUTICS, INC. (CA) 2017-01-12 US disclosed
WO-2016174062-A1 METHOD AND KIT FOR DISCHARGING AGROCHEMICAL PRODUCTS FROM TRANSPORT CONTAINERS. RELATED PRODUCTS ARYSTA LIFESCIENCE BENELUX SPRL (BE) 2016-11-03 WO disclosed
US-20160222020-A1 NOVEL TRICYCLIC COMPOUNDS ABBVIE INC. (US) 2016-08-04 US disclosed
CN-103416416-B Bactericidal composition containing tiadinil Shaanxi Welch Crop Protection Co.,Ltd. (CN) 2016-05-18 CN disclosed
WO-2016005318-A1 SYNTHESIS AND USE OF AMINO LIPIDS INCELLA GMBH (DE) 2016-01-14 WO disclosed
EP-2966068-A1 Synthesis and use of amino lipids Incella GmbH (DE) 2016-01-13 EP disclosed
EP-2961736-A1 INHIBITORS OF HISTONE DEMETHYLASES Epitherapeutics ApS (DK) 2016-01-06 EP disclosed
WO-2015057847-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS CERULEAN PHARMA INC. (US) 2015-04-23 WO disclosed
EP-2854527-A1 STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE se ma Gesellschaft für Innovationen mbH (DE) 2015-04-08 EP disclosed
EP-2817345-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS Cerulean Pharma Inc. (US) 2014-12-31 EP disclosed
EP-2817287-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF Protiva Biotherapeutics Inc. (CA) 2014-12-31 EP disclosed
WO-2014131777-A1 INHIBITORS OF HISTONE DEMETHYLASES EPITHERAPEUTICS APS (DK) 2014-09-04 WO disclosed
EP-1521733-B1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR PFIZER PROD INC (US) 2014-08-20 EP disclosed
US-20140037573-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS CERULEAN PHARMA INC (US) 2014-02-06 US disclosed
WO-2013175461-A1 STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE se ma Gesellschaft für Innovationen mbH (DE) 2013-11-28 WO disclosed
WO-2013126803-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF PROTIVA BIOTHERAPEUTICS INC. (CA) 2013-08-29 WO disclosed
WO-2013126564-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS CERULEAN PHARMA INC. (US) 2013-08-29 WO disclosed
US-20130216497-A1 NOVEL TRICYCLIC COMPOUNDS ABBOTT LABORATORIES 2013-08-22 US disclosed
EP-2616443-A1 PHTALAZINE DERIVATIVES AS JAK1 INHIBITORS Exelixis, Inc. (US) 2013-07-24 EP disclosed
US-8426411-B2 Tricyclic compounds ABBOTT LABORATORIES (US) 2013-04-23 US disclosed
EP-2506716-A1 NOVEL TRICYCLIC COMPOUNDS Abbott Laboratories (US) 2012-10-10 EP disclosed
CN-102498095-A Indoline derivatives TOKYO INST TECH 2012-06-13 CN disclosed
US-8173653-B2 Pyridiazinone derivatives for the treatment of tumours MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-05-08 US disclosed
WO-2012037132-A1 PHTALAZINE DERIVATIVES AS JAK1 INHIBITORS EXELIXIS, INC. (US) 2012-03-22 WO disclosed
US-20110311474-A1 Novel Tricyclic Compounds ABBOTT LABORATORIES (US) 2011-12-22 US disclosed
US-7553877-B2 Use of 2-hydroxy-1,2,3,4,4a,9,10,10a-octahydrophenanthrene compounds glucocorticoid receptor agonists to treat certain inflammatory conditions such as arthritis, asthma PFIZER, INC. (US) 2009-06-30 US disclosed
US-20080293719-A1 Pyridiazinone Derivatives for the Treatment of Tumours MERCK PATENT GESELLSCHAFT (DE) 2008-11-27 US disclosed
US-7138406-B2 Antiinflammatory agents; antiallergens; vision defects; anticancer agents; gastrointestinal disorders PFIZER, INC. (US) 2006-11-21 US disclosed
US-20060247264-A1 Use of 2-hydroxy-1,2,3,4,4a,9,10,10a-octahydrophenanthrene compounds glucocorticoid receptor agonists to treat certain inflammatory conditions such as arthritis, asthma PFIZER INC 2006-11-02 US disclosed
US-20060159772-A1 Fungicidal compositions ISAGRO S.P.A. (IT) 2006-07-20 US disclosed
EP-1565057-A2 FUNGICIDAL COMPOSITIONS CONTAINING AT LEAST ONE SALT OF PHOSPHOROUS ACID AND AT LEAST A SECOND FUNGICIDAL COMPONENT ISAGRO S.p.A. (IT) 2005-08-24 EP disclosed
EP-1521733-A1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR Pfizer Products Inc. (US) 2005-04-13 EP disclosed
CN-1191257-C Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them SERVIER LAB (FR) 2005-03-02 CN disclosed
EP-1370141-B1 NOVEL FUNGICIDE COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE AND PROPAMOCARB DERIVATIVE BAYER CROPSCIENCE SA (FR) 2005-01-05 EP disclosed
US-20040138262-A1 Antiinflammatory agents; antiallergens; vision defects; anticancer agents; gastrointestinal disorders PFIZER INC. 2004-07-15 US disclosed
WO-2004047540-A2 FUNGICIDAL COMPOSITIONS CONTAINING AT LEAST ONE SALT OF PHOSPHOROUS ACID AND AT LEAST A SECOND FUNGICIDAL COMPONENT ISAGRO S.P.A. (IT) 2004-06-10 WO disclosed
EP-1383737-A1 PROCESS FOR THE PREPARATION OF ALKYL-N-(3-DIMETHYLAMINO)ALKYLCARBAMATES Bayer CropScience GmbH (DE) 2004-01-28 EP disclosed
WO-2004005229-A1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR PFIZER PRODUCTS INC. (US) 2004-01-15 WO disclosed
US-6667414-B2 Renin inhibitors; hypertensive agents PHARMACIA CORPORATION 2003-12-23 US disclosed
EP-1370141-A1 NOVEL FUNGICIDE COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE AND PROPAMOCARB DERIVATIVE Bayer CropScience S.A. (FR) 2003-12-17 EP disclosed
EP-0874809-B1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-08-27 EP disclosed
CN-1437604-A Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-08-20 CN disclosed
US-20030144542-A1 Use of propargyl glycine amino propargyl diol compounds for treatment of renal failure HANSON GUNNAR J (US) 2003-07-31 US disclosed
US-20030135066-A1 Use of propargyl glycine amino propargyl diol compounds for treatment of congestive heart failure HANSON GUNNAR J (US) 2003-07-17 US disclosed
US-20030130522-A1 Use of propargyl glycine amino propargyl diol compounds for prevention of hypertension HANSON GUNNAR J (US) 2003-07-10 US disclosed
EP-1292597-A1 CARBAMATE AND THIOCARBAMATE PODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Les Laboratoires Servier (FR) 2003-03-19 EP disclosed
WO-2002090322-A1 PROCESS FOR THE PREPARATION OF ALKYL-N-(3-DIMETHYLAMINO)ALKYLCARBAMATES BAYER CROPSCIENCE GMBH (DE) 2002-11-14 WO disclosed
WO-2002069714-A1 NOVEL FUNGICIDE COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE AND PROPAMOCARB DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2002-09-12 WO disclosed
WO-2001098307-A1 CARBAMATE AND THIOCARBAMATE PODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LES LABORATOIRES SERVIER (FR) 2001-12-27 WO disclosed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US disclosed
EP-1095940-A2 Derivatives of 9-(3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphto[2,3-d][1,3]dioxol-6(5aH)-one, method for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2001-05-02 EP disclosed
US-6127411-A USE AGAINST PHYTOPHTHORA INFESTANS ON OR IN POTATO PLANTS OR TUBERS; APPLYING TO SEEDS OR TUBERS A MIXTURE OF A 2-ALKOXYIMINOACETAMIDE, AN ALKYLENE BIS-DITHIOCARBAMATE COMPLEX SALT AND A THIOPHANATE GUSTAFSON, INC. (US) 2000-10-03 US disclosed
US-6020368-A MICROBIOCIDES HINKS JEREMY DAVID (US) 2000-02-01 US disclosed
EP-0874809-A1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 1998-11-04 EP disclosed
WO-1997025309-A1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 1997-07-17 WO disclosed
US-5559120-A IMMUNOSUPPRESSANTS, ANTIINFLAMMATORY AGENTS, FUNGICIDES AND ANTITUMOR AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-09-24 US disclosed
US-5530121-A IMMUNOSUPPRESSANTS, ANTIINFLAMMATORY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-06-25 US disclosed
US-5530007-A ANTITUMOR, ANTIINFLAMMATORY, ANTIFUNGAL, ANTIPROLIFERATIVE, IMMUNOSUPPRESSIVE AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-06-25 US disclosed
EP-0555628-B1 Process for preparing isocyanates NIPPON CATALYTIC CHEM IND (JP) 1996-05-29 EP disclosed
US-5508399-A USEFUL AS IMMUNOSUPPRESSANT, ANTIINFLAMMATORY, ANTIFUNGAL, ANTIPROLIFERATIVE AND ANTIUMOR AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-04-16 US disclosed
US-5488160-A LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS CIBA-GEIGY CORPORATION (US) 1996-01-30 US disclosed
US-5480989-A Carbamates of rapamycin AMERICAN HOME PRODUCTS CORPORATION (US) 1996-01-02 US disclosed
US-5451700-A Leukotriene inhibitors CIBA-GEIGY CORPORATION (US) 1995-09-19 US disclosed
EP-0518819-B1 Amidino compounds, their manufacture and use as medicament CIBA GEIGY AG (CH) 1995-08-02 EP disclosed
US-5326903-A Thermal decomposition of carbamate NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
EP-0219756-B1 Acrylic amides SHELL INT RESEARCH (NL) 1994-01-05 EP disclosed
EP-0555628-A2 Process for preparing isocyanates NIPPON SHOKUBAI CO., LTD. (JP) 1993-08-18 EP disclosed
WO-1993009108-A1 AMINO ACYL AMINO PROPARGYL DIOL COMPOUNDS FOR TREATMENT OF HYPERTENSION G.D. SEARLE & CO. (US) 1993-05-13 WO disclosed
EP-0518819-A2 Amidino compounds, their manufacture and use as medicament CIBA-GEIGY AG (CH) 1992-12-16 EP disclosed
US-4910200-A Agricultural fungicide CELAMERCK GMBH & CO. KG (DE) 1990-03-20 US disclosed
EP-0120321-B1 ACRYLIC-ACID AMIDES, THEIR PREPARATION AND USE Shell Agrar GmbH & Co. KG (DE) 1988-10-05 EP disclosed
US-4753934-A Acrylic acid heterocyclic amides, fungicidal compositions and use CELAMERCK GMBH & CO. KG (DE) 1988-06-28 US disclosed
US-4400312-A WATER, A HYDROXIDE, AND A DIALKYLAMINO DITHIO CARBAMIC ACID, A MERCAPTO ALKANONE, OR A 3-HYDROXYTHIETANE PHILLIPS PETROLEUM COMPANY (US) 1983-08-23 US disclosed
US-4108885-A Salts of thiocarbamic esters with fungicidal and fungistatic action SCHERING AG (DE) 1978-08-22 US disclosed
US-4108885-A Salts of thiocarbamic esters with fungicidal and fungistatic action SCHERING AG (DE) 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (21 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247264-A1 Use of 2-hydroxy-1,2,3,4,4a,9,10,10a-octahydrophenanthrene compounds glucocorticoid receptor agonists to treat certain inflammatory conditions such as arthritis, asthma NR3C1, NR3C2, LTB4R2 DNM1 4430/4885KDM4E 2328/4885PAOX 844/4885
US-20030144542-A1 Use of propargyl glycine amino propargyl diol compounds for treatment of renal failure REN, AGTR1, GRHPR DNM1 735/4885KDM4E 724/4885PAOX 419/4885
US-20140037573-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS SYNCRIP, EXOSC5, EXOSC9 DNM1 799/4885KDM4E 4539/4885PAOX 3016/4885
US-20040138262-A1 Antiinflammatory agents; antiallergens; vision defects; anticancer agents; gastrointestinal disorders NR3C1, MC2R, FPR1 DNM1 3125/4885KDM4E 4711/4885PAOX 1958/4885
US-20220204485-A1 STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS TTR, MAP1LC3B, SAAL1 DNM1 2262/4885KDM4E 4575/4885PAOX 4238/4885
US-20030135066-A1 Use of propargyl glycine amino propargyl diol compounds for treatment of congestive heart failure REN, AGTR1, AGTR2 DNM1 942/4885KDM4E 1257/4885PAOX 698/4885
US-20170007702-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF NPC1L1, LIPA, LDLR DNM1 1380/4885KDM4E 4445/4885PAOX 1629/4885
US-20200306378-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF NPC1L1, LIPA, LDLR DNM1 1380/4885KDM4E 4445/4885PAOX 1629/4885
US-20210061813-A1 NOVEL TRICYCLIC COMPOUNDS CYP11B2, CYP11B1, ABCB1 DNM1 4588/4885KDM4E 4131/4885PAOX 2410/4885
US-20230109183-A1 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF NPC1L1, LIPA, LDLR DNM1 1380/4885KDM4E 4445/4885PAOX 1629/4885
US-20210238210-A1 ANTIVIRAL COMPOUNDS ZC3HAV1, SARS1, ZC3HAV1L DNM1 1902/4885KDM4E 2111/4885PAOX 4068/4885
US-11236071-B1 Farnesoid X receptor agonists and uses thereof NR1H4, NR1H2, NR1H3 DNM1 1208/4885KDM4E 4790/4885PAOX 116/4885
US-20030130522-A1 Use of propargyl glycine amino propargyl diol compounds for prevention of hypertension REN, AGTR1, GRHPR DNM1 998/4885KDM4E 755/4885PAOX 408/4885
US-20160222020-A1 NOVEL TRICYCLIC COMPOUNDS CYP11B2, CYP11B1, ABCB1 DNM1 4588/4885KDM4E 4131/4885PAOX 2410/4885
US-20170204076-A1 SYNTHESIS AND USE OF AMINO LIPIDS ACSL4, PYM1, LPAR4 DNM1 1719/4885KDM4E 389/4885PAOX 125/4885
US-20110311474-A1 Novel Tricyclic Compounds CYP11B2, CYP11B1, ABCB1 DNM1 4588/4885KDM4E 4131/4885PAOX 2410/4885
US-20130216497-A1 NOVEL TRICYCLIC COMPOUNDS CYP11B2, CYP11B1, ABCB1 DNM1 4588/4885KDM4E 4131/4885PAOX 2410/4885
US-10561732-B2 Trialkyl cationic lipids and methods of use thereof NPC1L1, LIPA, LDLR DNM1 1380/4885KDM4E 4445/4885PAOX 1629/4885
US-20080293719-A1 Pyridiazinone Derivatives for the Treatment of Tumours MET, RET, ERBB2 DNM1 3228/4885KDM4E 1695/4885PAOX 1922/4885
US-11945806-B2 Stabilization of amyloidogenic immunoglobulin light chains TTR, MAP1LC3B, SAAL1 DNM1 2262/4885KDM4E 4575/4885PAOX 4238/4885
US-11773121-B2 Antiviral compounds ZC3HAV1, SARS1, ZC3HAV1L DNM1 1902/4885KDM4E 2111/4885PAOX 4068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.