SCHEMBL205041

SCHEMBL205041

Nc1ccc(C(c2cccc(N)c2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
MAPK1 P28482 2/20 0.59
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CYP3A4 P08684 2/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
KIF11 P52732 2/20 0.41
MAOB P27338 2/20 0.38
PTGS1 P23219 4/20 0.37
CYP19A1 P11511 2/20 0.37
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7637720 1.00 TSHR (0.59) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL29492482 0.96 TSHR (0.63) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL201709 0.96 TSHR (0.63) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL202407 0.92 TSHR (0.47) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL10493904 0.92 TSHR (0.68) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL126398 0.92 TSHR (0.68) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL29373758 0.92 TSHR (0.68) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL29799449 0.92 TSHR (0.68) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL8582903 0.90 TSHR (0.61) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL9350813 0.90 ALDH1A1 (0.49) TSHRMAPK1CYP3A4MAOBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315666-B Transparent polymer film, electronic device including the same, and composition 三星电子株式会社 2020-03-10 CN claimed
CN-106009664-B Compositions, composites prepared therefrom, and films and electronic devices including the same 三星电子株式会社 2020-02-04 CN claimed
US-9975997-B2 Compositions, composites prepared therefrom, and films and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-22 US claimed
US-20160280857-A1 COMPOSITIONS, COMPOSITES PREPARED THEREFROM, AND FILMS AND ELECTRONIC DEVICES INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-09-29 US claimed
US-20160009862-A1 TRANSPARENT POLYMER FILM AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-01-14 US claimed
US-6040418-A FLUORINATED POLYMIDES COMPRISING UNITS OF 2,2',5,5',6,6'-HEXAFLUOROBIPHENYL-3,3',4,4'-TETRACARBOXYLIC DIANHYDRIDE AND AROMATIC DIAMINE UBE INDUSTRIES, LTD. (JP) 2000-03-21 US claimed
EP-0594591-A1 GAS SEPARATION MEMBRANES COMPRISING MISCIBLE BLENDS OF POLYIMIDE POLYMERS HOECHST CELANESE CORPORATION (US) 1994-05-04 EP claimed
EP-0594591-A4 GAS SEPARATION MEMBRANES COMPRISING MISCIBLE BLENDS OF POLYIMIDE POLYMERS. HOECHST CELANESE CORP (US) 1993-05-07 EP claimed
US-5061784-A POLYIMIDES OF IMPROVED SOLUBILITY AND PROCESSING CHARACTERISTICS HOECHST CELANESE CORPORATION (US) 1991-10-29 US claimed
WO-1991015285-A1 GAS SEPARATION MEMBRANES COMPRISING MISCIBLE BLENDS OF POLYIMIDE POLYMERS HOECHST CELANESE CORPORATION (US) 1991-10-17 WO claimed
EP-0385306-A1 Intermediate molecular weight polyimides and method for their preparation and articles therefrom HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
EP-0385303-A1 Shaped articles from polyamide-imide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
US-4954610-A SOLVENT, HEAT, OXIDATION, AND CHEMICAL RESISTANCE HOECHST CELANESE CORP. (US) 1990-09-04 US claimed
US-4954609-A CYCLIZED POLYAMIDE, NO ENDCAPPING HOECHST CELANESE CORP. (US) 1990-09-04 US claimed
US-4952669-A AND AN AROMATIC TETRACARBOXYLIC ACID; IMPROVED SOLUBILITY; MELT SPINNING; FIBERS; FILMS; COMPRESSION MOLDINGS HOECHST CELANESE CORP. (US) 1990-08-28 US claimed
US-4933132-A From aromatic dianhydride and aromatic diamine, at least one of which contains a trifluoromethane group HOECHST CELANESE CORP. (US) 1990-06-12 US claimed
EP-0361415-A1 Polymers prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane HOECHST CELANESE CORPORATION (US) 1990-04-04 EP claimed
EP-0361416-A1 Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane HOECHST CELANESE CORPORATION (US) 1990-04-04 EP claimed
EP-0361413-A1 Copolyimides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane HOECHST CELANESE CORPORATION (US) 1990-04-04 EP claimed
US-4914180-A Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane HOECHST CELANESE CORPORATION (US) 1990-04-03 US claimed