SCHEMBL126398

SCHEMBL126398

Nc1cccc(C(c2cccc(N)c2)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
MAPK1 P28482 1/20 0.68
CYP3A4 P08684 2/20 0.48
CASP1 P29466 1/20 0.48
RECQL P46063 1/20 0.48
ALDH1A1 P00352 4/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA14 Q9ULX7 1/20 0.39
PTGS1 P23219 3/20 0.39
MAOA P21397 2/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
LMNA P02545 2/20 0.35
POLB P06746 2/20 0.35
GAA P10253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29799449 1.00 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL10493904 1.00 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29373758 1.00 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29492476 0.98 TSHR (0.65) TSHRMAPK1CYP3A4CASP1RECQL
Hydrochloric Acid SCHEMBL8646815 0.98 TSHR (0.65) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL203354 0.98 TSHR (0.65) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29492482 0.96 TSHR (0.63) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL201709 0.96 TSHR (0.63) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL8582903 0.94 TSHR (0.61) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL27144624 0.94 TSHR (0.61) TSHRMAPK1CYP3A4CASP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI ADVANCED MAT CO LTD (KR) 2026-04-02 US claimed
EP-4714998-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI Advanced Materials Co., Ltd. (KR) 2026-03-25 EP claimed
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI ADVANCED MAT CO LTD (KR) 2026-03-05 US claimed
US-12522704-B2 Polyimide film having high dimensional stability and manufacturing method therefor PI ADVANCED MATERIALS CO., LTD. (KR) 2026-01-13 US claimed
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR PL ADVANCED MAT CO LTD (KR) 2026-01-08 US claimed
US-12503596-B2 Low-dielectric-constant polyimide composite powder, and method for producing same PI ADVANCED MATERIALS CO., LTD. 2025-12-23 US claimed
EP-4626991-A1 POLYIMIDE VARNISH FOR COATING CONDUCTOR WITH IMPROVED HEAT DISSIPATION FOR COATING CONDUCTOR AND POLYIMIDE COATING MATERIAL COMPRISING THE SAME PI Advanced Materials Co., Ltd. (KR) 2025-10-08 EP claimed
US-20250230282-A1 MANUFACTURING METHOD OF POLYIMIDE POWDER AND POLYIMIDE POWDER MANUFACTURED BY THE SAME PI ADVANCED MAT CO LTD (KR) 2025-07-17 US claimed
EP-0299865-A2 Process for preparing low dielectric polyimides NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-01-18 EP claimed
EP-0297570-A2 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP claimed
EP-0129562-B1 SOLAR CELL COMPRISING A PROTECTIVE POLYIMIDE COATING AND METHOD FOR PROTECTING SOLAR CELLS Hughes Aircraft Company (US) 1988-01-13 EP claimed
EP-0247084-A1 METHOD OF PREPARING HIGH MOLECULAR WEIGHT POLYIMIDE, PRODUCT AND USE Hughes Aircraft Company (US) 1987-12-02 EP claimed
WO-1987003289-A1 METHOD OF PREPARING HIGH MOLECULAR WEIGHT POLYIMIDE, PRODUCT AND USE HUGHES AIRCRAFT COMPANY (US) 1987-06-04 WO claimed
US-4661650-A Solar cell coated with high molecular weight polyimide HUGHES AIRCRAFT COMPANY (US) 1987-04-28 US claimed
US-4645824-A Method of preparing high molecular weight polyimide, product and use HUGHES AIRCRAFT COMPANY (US) 1987-02-24 US claimed
US-4592925-A Polyimide composition and method for protecting photoreactive cells HUGHES AIRCRAFT COMPANY (US) 1986-06-03 US claimed
EP-0129562-A1 Solar cell comprising a protective polyimide coating and method for protecting solar cells. HUGHES AIRCRAFT CO (US) 1985-01-02 EP claimed
WO-1984002529-A1 POLYIMIDE COMPOSITION AND METHOD FOR PROTECTING PHOTOREACTIVE CELLS HUGHES AIRCRAFT CO (US) 1984-07-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF SMURF1, TET1, VCL TSHR 2046/4885MAPK1 2373/4885CYP3A4 4110/4885
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME AOC1, AOC2, DDT TSHR 2535/4885MAPK1 336/4885CYP3A4 4599/4885
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM CDH1, PBRM1, ITGA1 TSHR 3634/4885MAPK1 1725/4885CYP3A4 3894/4885
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR MALT1, CDH1, TET1 TSHR 2267/4885MAPK1 1991/4885CYP3A4 2008/4885
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PARG, PARN, PUF60 TSHR 3774/4885MAPK1 1754/4885CYP3A4 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.