Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.32 |
| ▸ | CA2 | P00918 | 8/20 | 0.32 |
| ▸ | CA12 | O43570 | 7/20 | 0.32 |
| ▸ | CA9 | Q16790 | 6/20 | 0.32 |
| ▸ | CA7 | P43166 | 4/20 | 0.32 |
| ▸ | CA6 | P23280 | 3/20 | 0.32 |
| ▸ | CA5A | P35218 | 3/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3018155 | 0.79 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27833603 | 0.79 | POLB (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27698205 | 0.78 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL28253552 | 0.67 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL489962 | 0.67 | LMNA (0.48) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2616842 | 0.66 | — | — | |
| SCHEMBL8466464 | 0.66 | — | — | |
| SCHEMBL486467 | 0.64 | — | — | |
| SCHEMBL13316187 | 0.64 | TSHR (0.35) | ALDH1A1 | |
| Formamide SCHEMBL23636189 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377493-A1 | PURINONES AS UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITORS | Forma Therapeutics, Inc. (US) | 2018-09-26 | — | — | EP | claimed |
| CN-108473495-A | Purinones as ubiquitin-specific protease 1 inhibitors | 福马治疗有限公司 | 2018-08-31 | — | — | CN | claimed |
| CN-104507944-B | Pteridines as FGFR inhibitors | 阿斯特克斯治疗有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-102796081-A | Pyrimidine sulphonamide derivatives as chemokine receptor modulators | ASTRAZENECA AB | 2012-11-28 | — | — | CN | disclosed |
| CN-101048401-B | Pyrimidine sulfonamide derivatives as chemokine receptor modulators | ASTRAZENECA AB | 2012-09-12 | — | — | CN | disclosed |
| CN-100345829-C | Pyrimidyl sulphone amide derivatives as chemokine receptor modulators | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | disclosed |
| CN-1681795-A | Pyrimidyl sulfonamide derivatives as chemokine receptor modulators | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |