SCHEMBL20506789

SCHEMBL20506789

O=C(O)CN(CC(=O)O)[C@@H]1CCC[C@H]1N(CC(=O)O)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC18A3 Q16572 1/20 0.45
▸ MEN1 O00255 4/20 0.44
▸ KMT2A Q03164 4/20 0.44
▸ MAPK1 P28482 1/20 0.42
▸ AGER Q15109 3/20 0.42
▸ MTNR1A P48039 1/20 0.42
▸ ALDH1A1 P00352 5/20 0.41
▸ HPGD P15428 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ CTSD P07339 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ KCNA5 P22460 1/20 0.39
▸ GLA P06280 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20506803 0.97 SLC18A3 (0.49) SLC18A3MEN1KMT2AMAPK1AGER
SCHEMBL20506805 0.97 SLC18A3 (0.49) SLC18A3MEN1KMT2AMAPK1AGER
SCHEMBL29761165 0.97 SLC18A3 (0.49) SLC18A3MEN1KMT2AMAPK1AGER
SCHEMBL22593578 0.84 CA2 (0.41) SLC18A3MEN1KMT2AALDH1A1HPGD
SCHEMBL20506802 0.84 MEN1 (0.41) MEN1KMT2AALDH1A1CTSDKDM4E
SCHEMBL30329419 0.81 CA2 (0.40) SLC18A3MEN1KMT2AALDH1A1CTSD
SCHEMBL27398620 0.81 SLC18A3 (0.38) SLC18A3MEN1KMT2AMAPK1ALDH1A1
SCHEMBL22815239 0.81 SLC18A3 (0.38) SLC18A3MEN1KMT2AMAPK1ALDH1A1
SCHEMBL20506783 0.81 ABCB1 (0.46) SLC18A3MEN1KMT2AMAPK1ALDH1A1
SCHEMBL26483111 0.80 KMT2A (0.46) SLC18A3KMT2AALDH1A1HPGDKCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11420910-B2 Methods for low temperature fluorine-18 radiolabeling of biomolecules KATHOLIEKE UNIVERSITET LEUVEN (BE) 2022-08-23 — — US disclosed
EP-3212610-B1 METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES UNIV LEUVEN KATH (BE) 2020-10-28 — — EP disclosed
US-20180273441-A1 METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2018-09-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180273441-A1 METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES H1-3, H1-0, H1-2 SLC18A3 176/4885MEN1 532/4885KMT2A 480/4885
US-11420910-B2 Methods for low temperature fluorine-18 radiolabeling of biomolecules H1-3, H1-0, H1-2 SLC18A3 184/4885MEN1 540/4885KMT2A 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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