Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22593578 | 0.90 | CA2 (0.41) | CA2SLC18A3SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL22815239 | 0.86 | SLC18A3 (0.38) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL27398620 | 0.86 | SLC18A3 (0.38) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL29761165 | 0.84 | SLC18A3 (0.49) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL20506803 | 0.84 | SLC18A3 (0.49) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL20506805 | 0.84 | SLC18A3 (0.49) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL23085113 | 0.83 | SLC18A3 (0.35) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL25162267 | 0.83 | SLC18A3 (0.35) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL27398776 | 0.83 | SLC18A3 (0.35) | SLC18A3SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL25703421 | 0.82 | SIGMAR1 (0.37) | SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4412996-A1 | RADIOLABELLED FIBROBLAST ACTIVATION PROTEIN LIGANDS | Philochem AG (CH) | 2024-08-14 | — | — | EP | claimed |
| WO-2023057457-A1 | RADIOLABELLED FIBROBLAST ACTIVATION PROTEIN LIGANDS | PHILOCHEM AG (CH) | 2023-04-13 | — | — | WO | claimed |
| EP-4412996-A1 | RADIOLABELLED FIBROBLAST ACTIVATION PROTEIN LIGANDS | Philochem AG (CH) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023057457-A1 | RADIOLABELLED FIBROBLAST ACTIVATION PROTEIN LIGANDS | PHILOCHEM AG (CH) | 2023-04-13 | — | — | WO | disclosed |