SCHEMBL20506802

SCHEMBL20506802

O=C(O)CN(CC(=O)O)[C@@H]1CC=CC[C@H]1N(CC(=O)O)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ CTSD P07339 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ HSD17B10 Q99714 2/20 0.38
▸ TSHR P16473 1/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ CA12 O43570 1/20 0.38
▸ CA9 Q16790 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ AKR1B1 P15121 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ SLC6A2 P23975 1/20 0.36
▸ SLC6A4 P31645 1/20 0.36
▸ SLC6A3 Q01959 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20506789 0.84 SLC18A3 (0.45) MEN1KMT2ACTSDALDH1A1NPSR1
SCHEMBL20506803 0.84 SLC18A3 (0.49) MEN1KMT2ACTSDALDH1A1NPSR1
SCHEMBL29761165 0.84 SLC18A3 (0.49) MEN1KMT2ACTSDALDH1A1NPSR1
SCHEMBL20506805 0.84 SLC18A3 (0.49) MEN1KMT2ACTSDALDH1A1NPSR1
SCHEMBL8837984 0.82 TDP1 (0.35) TSHRKDM4ETDP1LMNASLC6A2
SCHEMBL20506828 0.81 ABCB1 (0.46) KMT2A
SCHEMBL22593578 0.72 CA2 (0.41) MEN1KMT2ACTSDALDH1A1HSD17B10
SCHEMBL2563108 0.71 SLC6A2 (0.51) MEN1KMT2AALDH1A1NPSR1HSD17B10
SCHEMBL212272 0.70 AKR1B1 (0.52) MEN1KMT2AALDH1A1NPSR1TSHR
SCHEMBL28647724 0.69 CTSD (0.51) MEN1KMT2ACTSDALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11420910-B2 Methods for low temperature fluorine-18 radiolabeling of biomolecules KATHOLIEKE UNIVERSITET LEUVEN (BE) 2022-08-23 — — US disclosed
EP-3212610-B1 METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES UNIV LEUVEN KATH (BE) 2020-10-28 — — EP disclosed
US-20180273441-A1 METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2018-09-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180273441-A1 METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES H1-3, H1-0, H1-2 MEN1 532/4885KMT2A 480/4885CTSD 2169/4885
US-11420910-B2 Methods for low temperature fluorine-18 radiolabeling of biomolecules H1-3, H1-0, H1-2 MEN1 540/4885KMT2A 498/4885CTSD 2203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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