SCHEMBL2050847

SCHEMBL2050847

Sc1nsc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ EPAS1 Q99814 9/20 0.47
▸ GPR3 P46089 1/20 0.40
▸ EPHX2 P34913 1/20 0.39
▸ TP53 P04637 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CMA1 P23946 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30987223 0.75 MAPT (0.60) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL28563540 0.75 MAPT (0.60) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL11600529 0.74 MAPT (0.54) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL11654916 0.71 MAPT (0.56) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL446289 0.71 MAPT (0.56) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL3810651 0.71 MAPT (0.56) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL329569 0.71 MAPT (0.61) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL4204967 0.71 MAPT (0.56) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL329419 0.71 MAPT (0.56) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL18410587 0.71 MAPT (0.56) MAPTKDM4EALDH1A1HSD17B10EPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081323-A Wear-resistant impact-resistant high polymer floor and preparation process thereof 洁玛新材料股份有限公司 2024-12-06 — — CN claimed
JP-2010509488-A — — 2010-03-25 — — JP claimed
WO-2008061079-A9 FLUOROCARBON STABILIZERS HONEYWELL INT INC (US) 2008-07-31 — — WO claimed
US-20080157023-A1 Hydrofluoroalkene, an iodocarbon, a lubricant and a metal stabilizer; automotive air conditioning systems HONEYWELL INTERNATIONAL INC 2008-07-03 — — US claimed
WO-2008061079-A2 FLUOROCARBON STABILIZERS HONEYWELL INTERNATIONAL INC. (US) 2008-05-22 — — WO claimed
US-4242495-A COATINGS, MOLDINGS, FOAMS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-12-30 — — US claimed
US-12247004-B2 2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use Oxford Drug Design Limited (GB) 2025-03-11 — — US disclosed
CN-114846000-B 2-Amino-N- (amino-oxo-aryl-lambda 6-sulfinyl) acetamide compounds and therapeutic uses thereof 牛津药物设计有限公司 2025-01-03 — — CN disclosed
CN-119081323-A Wear-resistant impact-resistant high polymer floor and preparation process thereof 洁玛新材料股份有限公司 2024-12-06 — — CN disclosed
US-20230114875-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2023-04-13 — — US disclosed
EP-4077289-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2022-10-26 — — EP disclosed
WO-2021123237-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2021-06-24 — — WO disclosed
WO-2021123237-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2021-06-24 — — WO disclosed
EP-0291743-A1 Method for protecting copper from corrosion International Business Machines Corporation (US) 1988-11-23 — — EP disclosed
US-4731128-A Protection of copper from corrosion INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1988-03-15 — — US disclosed
US-4242495-A COATINGS, MOLDINGS, FOAMS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-12-30 — — US disclosed
US-4172032-A Polyphosphate-based industrial cooling water treatment NALCO CHEMICAL COMPANY (US) 1979-10-23 — — US disclosed
US-4134959-A NONTOXIC CHEMED CORPORATION (US) 1979-01-16 — — US disclosed
US-4101441-A AN AZOLE COMPOUND, ORGANOPHOSPHONIC ACID, A PHOSPHATE CHEMED CORPORATION (US) 1978-07-18 — — US disclosed
US-4098720-A ALKALI METAL NITRITE, CARBONATE, HYDROXIDE AND SILICATE, AND WATER SOLUBLE MERCAPTOBENZOTHIAZOLE CHEMED CORPORATION (US) 1978-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12247004-B2 2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use AARS1, ASNS, GARS1 MAPT 3525/4885KDM4E 1323/4885ALDH1A1 2000/4885
US-20230114875-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE AARS1, ASNS, GARS1 MAPT 3525/4885KDM4E 1323/4885ALDH1A1 2000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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