Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691525 | 0.83 | MAPT (0.55) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL18485267 | 0.83 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL9731178 | 0.78 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL14805661 | 0.78 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL18193688 | 0.78 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL10766120 | 0.75 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL2050847 | 0.74 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL15665083 | 0.74 | MAPT (0.42) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL2954045 | 0.74 | MAPT (0.42) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL30987223 | 0.73 | MAPT (0.60) | MAPTKDM4EALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070318-A | VINYL PYRIDINE COPOLYMER RUBBER, CONDENSATION | THE GENERAL TIRE & RUBBER COMPANY (US) | 1978-01-24 | — | — | US | disclosed |