Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12857051 | 0.85 | SMN1; SMN2 (0.35) | CES2CES1HTTPKMSMN1; SMN2 | |
| SCHEMBL10137810 | 0.74 | FFAR1 (0.44) | CES2CES1HTTPKMSMN1; SMN2 | |
| SCHEMBL9593285 | 0.72 | CES2 (0.36) | CES2CES1HTTPKMSMN1; SMN2 | |
| SCHEMBL14189053 | 0.69 | SMN1; SMN2 (0.39) | CES2CES1HTTPKMSMN1; SMN2 | |
| SCHEMBL8175703 | 0.67 | CES2 (0.68) | CES2CES1HTTPKMSMN1; SMN2 | |
| SCHEMBL661258 | 0.67 | CES2 (0.46) | CES2CES1HTTPKMSMN1; SMN2 | |
| Lithium Ion SCHEMBL5014708 | 0.67 | CA1 (0.52) | CES2CES1HTTPKMSMN1; SMN2 | |
| Lithium Ion SCHEMBL28408172 | 0.67 | CA1 (0.59) | CES2CES1HTTPKMSMN1; SMN2 | |
| SCHEMBL10137812 | 0.66 | SMN1; SMN2 (0.41) | CES2CES1PKMSMN1; SMN2MAPK1 | |
| SCHEMBL217793 | 0.65 | CES2 (0.43) | CES2CES1HTTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240000724-A1 | Compositions and Methods for Treatment or Prevention of Oral Mucositis | PATHWAYS BIOSCIENCE, LLC | 2024-01-04 | — | — | US | claimed |
| US-20240000724-A1 | Compositions and Methods for Treatment or Prevention of Oral Mucositis | PATHWAYS BIOSCIENCE, LLC | 2024-01-04 | — | — | US | disclosed |
| US-11786483-B2 | Compositions and methods for treatment or prevention of oral mucositis | PATHWAYS BIOSCIENCE, LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20200206156-A1 | Compositions and Methods for Treatment or Prevention of Oral Mucositis | PATHWAYS BIOSCIENCE, LLC | 2020-07-02 | — | — | US | disclosed |
| US-20180271803-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OR PREVENTION OF ORAL MUCOSITIS | PATHWAYS BIOSCIENCE, LLC | 2018-09-27 | — | — | US | disclosed |