Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135625 | 0.84 | CES2 (0.30) | CES2CES1MEN1KMT2A | |
| SCHEMBL20508995 | 0.72 | CES2 (0.39) | CES2CES1GAAHTTPKM | |
| SCHEMBL1344949 | 0.72 | PKM (0.46) | CES2CES1GAAMEN1KMT2A | |
| SCHEMBL8925773 | 0.71 | AKR1C3 (0.34) | CES2CES1 | |
| SCHEMBL10137810 | 0.70 | FFAR1 (0.44) | CES2CES1GAAHTTPKM | |
| SCHEMBL661258 | 0.70 | CES2 (0.46) | CES2CES1GAAMEN1KMT2A | |
| SCHEMBL8471692 | 0.69 | CES2 (0.40) | CES2CES1SMN1; SMN2 | |
| SCHEMBL10684699 | 0.69 | SMN1; SMN2 (0.39) | GAAHTTPKMSMN1; SMN2LMNA | |
| SCHEMBL336394 | 0.67 | CES2 (0.43) | CES2CES1GAAMEN1KMT2A | |
| SCHEMBL203915 | 0.67 | CES2 (0.43) | CES2CES1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210193-A | Bactericide | AMERICAN CYANAMID COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-4940710-A | 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0230053-A2 | 7-(Substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |