SCHEMBL2051092

SCHEMBL2051092

Cc1ccc(-c2[c]c3c(cc2)-c2ccc(-c4ccc(C)cc4)cc2C3)cc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
PDK2 Q15119 1/20 0.33
TDP2 O95551 6/20 0.33
METAP1 P53582 1/20 0.32
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717055 0.86 TDP2 (0.46) ESR1ESR2TDP2
SCHEMBL2046327 0.84 TDP2 (0.36) TDP2
SCHEMBL2051839 0.84 PTK2 (0.33) ESR1ESR2TDP2
SCHEMBL2047309 0.84 PARP10 (0.44) PDK2TDP2PGR
SCHEMBL2045017 0.81 MMP12 (0.36)
SCHEMBL2048603 0.79 MPL (0.41)
SCHEMBL2046466 0.79 NPSR1 (0.32)
SCHEMBL1905297 0.79 ESR1 (0.46) ESR1ESR2PDK2TDP2METAP1
SCHEMBL716718 0.78 MEN1 (0.31)
SCHEMBL2050790 0.75 GRIA1 (0.45) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110152463-A1 RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-23 US disclosed