SCHEMBL717055

SCHEMBL717055

[c]1c(-c2ccccc2)ccc2c1Cc1cc(-c3ccccc3)ccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 12/20 0.46
PARP10 Q53GL7 1/20 0.39
PARP11 Q9NR21 1/20 0.39
TYRO3 Q06418 1/20 0.37
NTRK2 Q16620 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
DYRK1B Q9Y463 1/20 0.37
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
XBP1 P17861 1/20 0.35
PTBP1 P26599 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
GALK1 P51570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2051092 0.86 ESR1 (0.36) TDP2ESR1ESR2
SCHEMBL216860 0.85 ALDH1A1 (0.38) NPC1LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL2047309 0.82 PARP10 (0.44) TDP2PARP10PARP11CLK4DYRK1B
SCHEMBL2051839 0.82 PTK2 (0.33) TDP2MMP12MMP13ESR1ESR2
SCHEMBL2046327 0.82 TDP2 (0.36) TDP2MEN1KMT2A
SCHEMBL2045017 0.80 MMP12 (0.36) MMP12MMP13NPC1MAPTRAB9A
SCHEMBL2047276 0.79 BCL2 (0.40) TDP2ESR1ESR2
SCHEMBL2051675 0.79 KIF11 (0.40) TDP2PARP10PARP11
SCHEMBL1482920 0.78 TDP2 (0.61) TDP2PARP10PARP11TYRO3NTRK2
SCHEMBL3136254 0.78 TDP2 (0.61) TDP2PARP10PARP11TYRO3NTRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945553-A Process for preparing a methylene-bridged biscyclopentadienyl compound TARGOR GMBH (DE) 1999-08-31 US claimed
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US disclosed
US-20230174883-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES EXXONMOBIL CHEMICAL PATENTS INC. 2023-06-08 US disclosed
WO-2023081325-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
WO-2023081327-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES CHEVRON ORONITE COMPANY LLC (US) 2023-05-11 WO disclosed
WO-2023081010-A1 POLYPROPYLENE VISCOSITY MODIFIERS AND LUBRICATING OILS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
CN-106661488-B Syndiotactic propylene polymers and lubricating oils containing the same 埃克森美孚化学专利公司 2021-04-09 CN disclosed
US-5962359-A Metallocene compound and its use as catalyst component TARGOR GMBH (DE) 1999-10-05 US disclosed
US-5945553-A Process for preparing a methylene-bridged biscyclopentadienyl compound TARGOR GMBH (DE) 1999-08-31 US disclosed
EP-0628577-B1 Silyl bridged metallocenes and use thereof PHILLIPS PETROLEUM CO (US) 1999-03-03 EP disclosed
EP-0875517-A1 Novel homopolymers of propylene exhibiting more than 50% syndiotacticity and more than 50 wt-% xylene solubles PHILLIPS PETROLEUM COMPANY (US) 1998-11-04 EP disclosed
EP-0832866-A2 Process for the preparation of methylene-bridged biscyclopentadienyl compounds TARGOR GmbH (DE) 1998-04-01 EP disclosed
US-5627118-A CATALYSTS FOR OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US disclosed
EP-0723971-A2 Metallocenes and their use as catalyst component HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-31 EP disclosed
US-5459218-A Containing fluorene ring PHILLIPS PETROLEUM COMPANY (US) 1995-10-17 US disclosed
US-5401817-A Syndiotactic polypropylene PHILLIPS PETROLEUM COMPANY (US) 1995-03-28 US disclosed
EP-0628577-A2 Silyl bridged metallocenes and use thereof PHILLIPS PETROLEUM COMPANY (US) 1994-12-14 EP disclosed