Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20511852 | 0.82 | CA1 (0.36) | TSHRKMT2AMIF | |
| SCHEMBL18669141 | 0.81 | GAA (0.41) | CYP1A2CYP2D6CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL20511864 | 0.77 | CA1 (0.32) | LMNA | |
| SCHEMBL10086053 | 0.69 | MIF (0.50) | LMNATSHRMEN1KMT2ATDP1 | |
| SCHEMBL20508164 | 0.61 | NFKB1 (0.43) | LMNAMEN1KMT2AHPGDCYP3A4 | |
| SCHEMBL14354362 | 0.58 | — | — | |
| SCHEMBL9296414 | 0.57 | NPSR1 (0.34) | LMNATSHRKMT2AMIFHTT | |
| SCHEMBL31295129 | 0.56 | BRD4 (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL25268709 | 0.55 | BRD4 (0.34) | LMNATSHR | |
| SCHEMBL25274007 | 0.55 | BRD4 (0.34) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601280-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018172480-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-27 | — | — | WO | disclosed |