Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18669101 | 0.84 | GAA (0.39) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL18669148 | 0.81 | GAA (0.43) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL18669211 | 0.81 | MTNR1A (0.34) | CYP1A2CYP2D6 | |
| SCHEMBL20511809 | 0.81 | LMNA (0.32) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9826015 | 0.75 | MIF (0.42) | GAACTSK | |
| SCHEMBL4949895 | 0.70 | GAA (0.55) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL26700057 | 0.70 | NFKB1 (0.38) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL571098 | 0.65 | BTK (0.50) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL20511852 | 0.65 | CA1 (0.36) | NFKB1NFKB2RELA | |
| SCHEMBL20377683 | 0.64 | GAA (0.56) | GAANFKB1NFKB2RELABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213032-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-04 | — | — | US | disclosed |
| US-11213032-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-04 | — | — | US | disclosed |
| CN-108026090-B | Isoxazoline substituted benzamides and analogs as pesticides | 先正达参股股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| EP-3353172-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-24 | — | — | EP | disclosed |
| EP-3353172-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-24 | — | — | EP | disclosed |
| US-20200037613-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-06 | — | — | US | disclosed |
| US-20200037613-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-06 | — | — | US | disclosed |
| EP-3601280-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018172480-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-27 | — | — | WO | disclosed |
| US-20180271096-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-27 | — | — | US | disclosed |
| EP-3353172-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | Syngenta Participations AG (CH) | 2018-08-01 | — | — | EP | disclosed |
| WO-2017050921-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017050921-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180271096-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | CYP2E1, CYP3A7, CYP4X1 | GAA 3261/4885NFKB1 3467/4885NFKB2 3932/4885 |
| US-11213032-B2 | Insecticidal compounds | DDT, ACHE, CYP2E1 | GAA 3099/4885NFKB1 1658/4885NFKB2 2273/4885 |
| US-20200037613-A1 | INSECTICIDAL COMPOUNDS | DDT, ACHE, CYP2E1 | GAA 2946/4885NFKB1 1430/4885NFKB2 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.