Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14999773 | 0.98 | GAA (0.53) | GAAADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL12963726 | 0.85 | GAA (0.51) | GAAADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL16985200 | 0.85 | CYP3A4 (0.56) | GAAMAPTALDH1A1RAB9ATSHR | |
| SCHEMBL29153467 | 0.83 | GAA (0.53) | GAAADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL13165681 | 0.83 | GAA (0.53) | GAAADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL5007923 | 0.82 | SLC2A1 (0.42) | GAAADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL3372005 | 0.81 | ALDH1A1 (0.57) | GAAMAPTALDH1A1HPGDHTT | |
| SCHEMBL27645827 | 0.81 | MEN1 (0.43) | GAAADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL17847346 | 0.80 | GAA (0.50) | GAAADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL12933389 | 0.80 | GAA (0.50) | GAAADRA2AADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381915-B1 | LACTAM COMPOUND DERIVATIVE AND APPLICATION THEREOF | NHWA PHARMA CORP (CN) | 2023-01-18 | — | — | EP | disclosed |
| EP-3483149-B1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | YUHAN CORP (KR) | 2021-01-13 | — | — | EP | disclosed |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | YUHAN CORPORATION (KR) | 2019-08-20 | — | — | US | disclosed |
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | YUHAN CORPORATION (KR) | 2019-05-16 | — | — | US | disclosed |
| EP-3483149-A1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Yuhan Corporation (KR) | 2019-05-15 | — | — | EP | disclosed |
| US-20180327397-A1 | LACTAM COMPOUND DERIVATIVE AND APPLICATION THEREOF | NHWA PHARMA. CORPORATION (CN) | 2018-11-15 | — | — | US | disclosed |
| EP-3381915-A1 | LACTAM COMPOUND DERIVATIVE AND APPLICATION THEREOF | NHWA Pharma Corporation (CN) | 2018-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | ILK, SBDS, BDKRB1 | GAA 4292/4885ADRA2A 3691/4885ADRA2C 3537/4885 |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | ILK, SBDS, BDKRB1 | GAA 4292/4885ADRA2A 3691/4885ADRA2C 3537/4885 |
| US-20180327397-A1 | LACTAM COMPOUND DERIVATIVE AND APPLICATION THEREOF | BACE1, QPCT, PSENEN | GAA 1134/4885ADRA2A 3189/4885ADRA2C 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.