Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514910 | 0.73 | KDM4E (0.44) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL20514856 | 0.69 | SMN1; SMN2 (0.36) | ALDH1A1ALOX15MAPT | |
| SCHEMBL660035 | 0.64 | ALDH1A1 (0.68) | ALDH1A1ALOX15POLBRECQLMAPT | |
| SCHEMBL3043384 | 0.63 | POLB (0.44) | ALDH1A1ALOX15POLBNQO2RECQL | |
| SCHEMBL5991959 | 0.62 | GRIA4 (0.63) | ALDH1A1ALOX15POLBNQO2RECQL | |
| SCHEMBL15247029 | 0.61 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTGRIA4KMT2A | |
| SCHEMBL1784068 | 0.60 | MAPT (0.39) | ALDH1A1ALOX15POLBNQO2RECQL | |
| SCHEMBL48208 | 0.60 | — | — | |
| SCHEMBL1267234 | 0.59 | MEN1 (0.57) | ALDH1A1POLBGRIA4KMT2AMEN1 | |
| SCHEMBL4887431 | 0.59 | CA1 (0.58) | ALDH1A1ALOX15POLBNQO2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-B1 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | BIOELECTRON TECH CORP (US) | 2018-10-03 | — | — | EP | claimed |