Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514856 | 0.81 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2MAPTTSHRMTNR1A | |
| SCHEMBL20514880 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL20514879 | 0.68 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPK1 | |
| SCHEMBL6707038 | 0.68 | KDM4E (0.50) | KDM4EF13A1ALDH1A1HIF1ASMN1; SMN2 | |
| SCHEMBL10592850 | 0.67 | KDM4E (0.84) | KDM4EF13A1ALDH1A1HIF1ASMN1; SMN2 | |
| SCHEMBL20514853 | 0.67 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL6845396 | 0.65 | KDM4E (0.72) | KDM4EF13A1ALDH1A1HIF1ASMN1; SMN2 | |
| SCHEMBL661278 | 0.65 | KDM4E (0.72) | KDM4EF13A1ALDH1A1HIF1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1421841 | 0.64 | KDM4E (0.70) | KDM4EF13A1ALDH1A1HIF1ASMN1; SMN2 | |
| SCHEMBL8107 | 0.64 | KDM4E (0.71) | KDM4EF13A1ALDH1A1HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-B1 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | BIOELECTRON TECH CORP (US) | 2018-10-03 | — | — | EP | claimed |