Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514853 | 0.85 | ALDH1A1 (0.35) | ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL20514871 | 0.77 | MEN1 (0.43) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1655312 | 0.70 | HTT (0.35) | ALDH1A1HTTSMN1; SMN2L3MBTL1DNM1 | |
| SCHEMBL20514910 | 0.68 | KDM4E (0.44) | ALDH1A1SMN1; SMN2MAPK1HSD17B10KDM4E | |
| SCHEMBL20514856 | 0.65 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL19347966 | 0.64 | CHRNB2 (0.52) | ALDH1A1HTTSMN1; SMN2L3MBTL1DNM1 | |
| SCHEMBL14557541 | 0.63 | DNM1 (0.46) | ALDH1A1HTTSMN1; SMN2L3MBTL1DNM1 | |
| SCHEMBL1414877 | 0.62 | — | — | |
| SCHEMBL1768371 | 0.61 | NOS2 (0.44) | DNM1 | |
| SCHEMBL1768376 | 0.61 | NOS2 (0.44) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-B1 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | BIOELECTRON TECH CORP (US) | 2018-10-03 | — | — | EP | claimed |