Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 18/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20515131 | 0.91 | HPSE (1.00) | HPSENPC1POLBCASP3RAB9A | |
| SCHEMBL20515146 | 0.87 | HPSE (0.77) | HPSENPC1RAB9AKDM4E | |
| SCHEMBL507169 | 0.84 | KDM4E (0.77) | HPSENPC1POLBCASP3RAB9A | |
| SCHEMBL9820079 | 0.84 | HPSE (0.72) | HPSEKDM4E | |
| SCHEMBL11626342 | 0.84 | HPSE (0.72) | HPSENPC1POLBCASP3RAB9A | |
| SCHEMBL5461475 | 0.84 | HPSE (0.72) | HPSENPC1RAB9AKDM4E | |
| SCHEMBL20515135 | 0.83 | HPSE (1.00) | HPSE | |
| SCHEMBL14581706 | 0.82 | HPSE (0.70) | HPSENPC1POLBCASP3RAB9A | |
| Methane SCHEMBL505763 | 0.82 | HPSE (0.70) | HPSENPC1POLBCASP3RAB9A | |
| Methane SCHEMBL5476423 | 0.82 | HPSE (0.70) | HPSENPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018177857-A1 | SYMMETRICAL 2-AMINOPHENYL-BENZAZOLYL-5-ACETATE COMPOUNDS AND THEIR USE AS ANTI-HEPARANASE | LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE (CH) | 2018-10-04 | — | — | WO | claimed |
| EP-3381907-A1 | SYMMETRICAL 2-AMINOPHENYL-BENZAZOLYL-5-ACETATE COMPOUNDS AND THEIR USE AS ANTI-HEPARANASE | Leadiant Biosciences SA (CH) | 2018-10-03 | — | — | EP | claimed |
| WO-2018177857-A1 | SYMMETRICAL 2-AMINOPHENYL-BENZAZOLYL-5-ACETATE COMPOUNDS AND THEIR USE AS ANTI-HEPARANASE | LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE (CH) | 2018-10-04 | — | — | WO | disclosed |
| EP-3381907-A1 | SYMMETRICAL 2-AMINOPHENYL-BENZAZOLYL-5-ACETATE COMPOUNDS AND THEIR USE AS ANTI-HEPARANASE | Leadiant Biosciences SA (CH) | 2018-10-03 | — | — | EP | disclosed |