Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 13/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461475 | 0.99 | HPSE (0.72) | HPSERAB9ANPC1MAPTKDM4E | |
| Methane SCHEMBL506232 | 0.87 | HPSE (0.70) | HPSEMAPTKDM4ETP53SMN1; SMN2 | |
| Methane SCHEMBL505763 | 0.87 | HPSE (0.70) | HPSERAB9ANPC1MAPTKDM4E | |
| SCHEMBL507169 | 0.87 | KDM4E (0.77) | HPSERAB9ANPC1KDM4EALDH1A1 | |
| Methane SCHEMBL25304065 | 0.86 | HPSE (0.69) | HPSERAB9ANPC1MAPTKDM4E | |
| SCHEMBL11626342 | 0.86 | HPSE (0.72) | HPSERAB9ANPC1MAPTKDM4E | |
| SCHEMBL9820079 | 0.86 | HPSE (0.72) | HPSEMAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL14581706 | 0.85 | HPSE (0.70) | HPSERAB9ANPC1KDM4EGAA | |
| SCHEMBL6818285 | 0.84 | NPC1 (0.67) | HPSERAB9ANPC1MAPTKDM4E | |
| SCHEMBL20515142 | 0.82 | HPSE (1.00) | HPSERAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043003-A1 | Novel compounds for the prophylaxis and treatment of inflammatory bowel diseases | HIKMA PHARMACEUTICALS CO., LTD. (JO) | 2007-02-22 | — | — | US | disclosed |
| EP-1688413-A1 | Benzoxazole derivatives for the prophylaxis and treatment of inflammatory bowel diseases | Hikma Pharmaceuticals Co. Ltd. (JO) | 2006-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043003-A1 | Novel compounds for the prophylaxis and treatment of inflammatory bowel diseases | SI, ALPI, VIP | HPSE 811/4885RAB9A 978/4885NPC1 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.