Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853034 | 0.98 | TDP1 (0.66) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL3434351 | 0.94 | RAB9A (0.69) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL22146533 | 0.94 | TDP1 (0.66) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL22832407 | 0.93 | TDP1 (0.59) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL12971078 | 0.93 | TDP1 (0.59) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11323600 | 0.89 | PKM (0.77) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL3434885 | 0.89 | RAB9A (0.58) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28286830 | 0.88 | TDP1 (0.79) | TDP1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15649870 | 0.88 | GAA (0.68) | TDP1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL160688 | 0.88 | ESR1 (0.69) | TDP1RAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10668130-B2 | Formulation for targeting cancer in humans and canines using chlorotoxin | RAMANA VIVEKANANDA (US) | 2020-06-02 | — | — | US | disclosed |
| US-10668113-B2 | Formulation for targeting cancer in humans and canines using venom | RAMANA VIVEKANANDA (US) | 2020-06-02 | — | — | US | disclosed |
| US-20180280473-A1 | FORMULATION FOR TARGETING CANCER IN HUMANS AND CANINES USING CHLOROTOXIN | RAMANA VIVEKANANDA (US) | 2018-10-04 | — | — | US | disclosed |
| US-20180280449-A1 | FORMULATION FOR TARGETING CANCER IN HUMANS AND CANINES USING VENOM | RAMANA VIVEKANANDA (US) | 2018-10-04 | — | — | US | disclosed |