SCHEMBL2853034

SCHEMBL2853034

O=C(OCCOc1ccccc1)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.66
RAB9A P51151 5/20 0.64
MAPT P10636 2/20 0.64
NPC1 O15118 4/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
HPGD P15428 2/20 0.63
ALDH1A1 P00352 2/20 0.63
KMT2A Q03164 2/20 0.63
KDM4E B2RXH2 1/20 0.63
MEN1 O00255 1/20 0.63
NFKB1 P19838 1/20 0.63
NFKB2 Q00653 1/20 0.63
RELA Q04206 1/20 0.63
HSD17B10 Q99714 1/20 0.63
PKM P14618 1/20 0.61
LMNA P02545 1/20 0.61
THRB P10828 1/20 0.59
MMP1 P03956 1/20 0.58
MMP12 P39900 1/20 0.58
PARP10 Q53GL7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20515482 0.98 TDP1 (0.63) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL3434351 0.96 RAB9A (0.69) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL22146533 0.96 TDP1 (0.66) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL22832407 0.95 TDP1 (0.59) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL12971078 0.95 TDP1 (0.59) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL3434885 0.91 RAB9A (0.58) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL11323600 0.91 PKM (0.77) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL15649870 0.90 GAA (0.68) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL160688 0.90 ESR1 (0.69) TDP1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL3827544 0.89 TDP1 (0.62) TDP1RAB9AMAPTNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365785-B2 Glycol ether aryl ester plasticizer EASTMAN CHEMICAL COMPANY (US) 2025-07-22 US claimed
US-20220227962-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2022-07-21 US claimed
EP-3990532-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER Eastman Chemical Company (US) 2022-05-04 EP claimed
CN-114008119-A Glycol ether aryl ester plasticizers 伊士曼化工公司 2022-02-01 CN claimed
WO-2020263593-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2020-12-30 WO claimed
EP-2162574-B8 A VISCOSE FIBER WITH MODIFIED PROPERTY AND A PROCESS FOR MAKING THEREFOR ADITYA BIRLA SCI & TECH CO LTD (IN) 2012-10-10 EP claimed
JP-2010532433-A 2010-10-07 JP claimed
JP-2010532434-A 2010-10-07 JP claimed
JP-2010532405-A 2010-10-07 JP claimed
US-20100204289-A1 VISCOSE FIBER WITH MODIFIED PROPERTY AND A PROCESS FOR MAKING THEREFOR ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD. (IN) 2010-08-12 US claimed
WO-2009057134-A2 A VISCOSE FIBER WITH MODIFIED PROPERTY AND A PROCESS FOR MAKING THEREFOR ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD. (IN) 2009-05-07 WO claimed
WO-2009057135-A2 ACRYLIC FIBER WITH MODIFIED PROPERTY AND A PROCESS FOR MAKING THEREFOR ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD. (IN) 2009-05-07 WO claimed
US-20080233067-A1 Method Of Making Enhanced Efficacy Antiperspirant Actives COLGATE-PALMOLIVE COMPANY (US) 2008-09-25 US claimed
WO-2008014505-A2 BLENDS FOR IMPROVED SOLUBILIZATION OF ACTIVE AND FUNCTIONAL ORGANIC COMPOUNDS ISP INVESTMENTS INC. (US) 2008-01-31 WO claimed
EP-1292274-A2 METHOD OF MAKING ENHANCED EFFICACY ANTIPERSPIRANT ACTIVES Colgate-Palmolive Company (US) 2003-03-19 EP claimed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US claimed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2001097768-A2 METHOD OF MAKING ENHANCED EFFICACY ANTIPERSPIRANT ACTIVES COLGATE-PALMOLIVE COMPANY (US) 2001-12-27 WO claimed
US-4556557-A NONIONIC SURFACTANT AND FUNGICIDE OR BACTERICIDE IN SALT SOLUTION REICHERT DIETRICH (DE) 1985-12-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365785-B2 Glycol ether aryl ester plasticizer DAGLA, DDT, PPARG TDP1 1253/4885RAB9A 4421/4885MAPT 1900/4885
US-20220227962-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER DAGLA, DDT, PPARG TDP1 1253/4885RAB9A 4421/4885MAPT 1900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.