Urea

Urea

SCHEMBL20515740

CCCCCCCCCCCCCCCCCC(=O)NN(CC)CCO.NC(N)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.46
HSP90AA1 P07900 1/20 0.44
FAAH O00519 6/20 0.43
TRPV1 Q8NER1 2/20 0.41
CNR2 P34972 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPK1 P28482 1/20 0.41
NAAA Q02083 1/20 0.40
SELP P16109 1/20 0.39
CNR1 P21554 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
SPHK1 Q9NYA1 1/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122541 0.95 DNM1 (0.50) DNM1HSP90AA1FAAHTRPV1CNR2
Acetic Acid SCHEMBL9844193 0.91 DNM1 (0.46) DNM1HSP90AA1FAAHMEN1KMT2A
Phosphoric Acid SCHEMBL9844412 0.89 DNM1 (0.45) DNM1HSP90AA1FAAHTRPV1CNR2
SCHEMBL28881097 0.89 DNM1 (0.50) DNM1HSP90AA1FAAHTRPV1CNR2
SCHEMBL28881076 0.89 DNM1 (0.50) DNM1HSP90AA1FAAHTRPV1CNR2
SCHEMBL5460718 0.89 DNM1 (0.53) DNM1HSP90AA1FAAHTRPV1CNR2
SCHEMBL5935452 0.87 TRPV1 (0.55) TRPV1CNR2MEN1KMT2ACNR1
Lactic Acid SCHEMBL9844034 0.85 FAAH (0.45) DNM1HSP90AA1FAAHMEN1KMT2A
SCHEMBL10792517 0.85 DNM1 (0.50) DNM1HSP90AA1FAAHTRPV1CNR2
SCHEMBL28881092 0.85 DNM1 (0.50) DNM1HSP90AA1FAAHTRPV1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10959937-B2 Oil-in-water type organopolysiloxane emulsion and method for producing same, cosmetic raw material, and cosmetic product DOW TORAY CO., LTD. (JP) 2021-03-30 US disclosed
US-20180280283-A1 OIL-IN-WATER TYPE ORGANOPOLYSILOXANE EMULSION AND METHOD FOR PRODUCING SAME, COSMETIC RAW MATERIAL, AND COSMETIC PRODUCT DOW TORAY CO., LTD. (JP) 2018-10-04 US disclosed