Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122541 | 0.90 | DNM1 (0.50) | FAAHMEN1KMT2AMAPK1DNM1 | |
| Acetic Acid SCHEMBL9844193 | 0.88 | DNM1 (0.46) | FAAHMEN1KMT2AMAPK1DNM1 | |
| Urea SCHEMBL20515740 | 0.85 | DNM1 (0.46) | FAAHMEN1KMT2AMAPK1DNM1 | |
| Phosphoric Acid SCHEMBL9844412 | 0.84 | DNM1 (0.45) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL28881076 | 0.84 | DNM1 (0.50) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL28881097 | 0.84 | DNM1 (0.50) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL5460718 | 0.83 | DNM1 (0.53) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL5935452 | 0.82 | TRPV1 (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6577915 | 0.81 | GPR84 (0.50) | FAAHMEN1KMT2ADNM1PLA2G2C | |
| SCHEMBL29174011 | 0.81 | DNM1 (0.50) | FAAHMEN1KMT2AMAPK1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410659-A2 | Method and composition to impart improved conditioning properties to the hair | HELENE CURTIS, INC. (US) | 1991-01-30 | — | — | EP | claimed |
| US-4976956-A | Water soluble and oil soluble quaternary ammonium compounds and amidoamine | HELENE CURTIS, INC. (US) | 1990-12-11 | — | — | US | claimed |