SCHEMBL2051590

SCHEMBL2051590

Cc1csc(-c2ccccc2Oc2nnc(Cl)cc2O)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.41
KMT2A Q03164 2/20 0.37
GLA P06280 1/20 0.36
PDE10A Q9Y233 1/20 0.36
MAPT P10636 3/20 0.35
POLB P06746 1/20 0.35
MIF P14174 1/20 0.34
TSHR P16473 1/20 0.34
HPGD P15428 3/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ADORA2A P29274 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2046732 0.79 KMT2A (0.53) KMT2AGLAMAPTPOLBHPGD
SCHEMBL2051550 0.78 NCOA1 (0.40) MAPTHPGDKDM4EHSD17B10ALDH1A1
SCHEMBL2051376 0.78 NPSR1 (0.41) ADRA1AKMT2AMAPTHPGDKDM4E
SCHEMBL2045759 0.77 ADRA2A (0.41) ADRA1AADORA2ACYP2E1CYP2A6CYP2B6
SCHEMBL2047940 0.76 MEN1 (0.47) KMT2AMAPTTSHRHPGDKDM4E
SCHEMBL2048850 0.75 TP53 (0.42) KMT2AMAPTPOLBTSHRHPGD
SCHEMBL2047088 0.74 RXRA (0.35) KMT2AMAPTHPGDKDM4EHSD17B10
SCHEMBL2047260 0.74 LMNA (0.46) KMT2AMAPTHPGDALDH1A1MEN1
SCHEMBL2051725 0.73 CA1 (0.40) KMT2AMAPTPOLBTSHRHPGD
SCHEMBL2053013 0.73 CA1 (0.44) KMT2AMAPTPOLBTSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964531-B2 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2011-06-21 US disclosed
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2010-02-18 US disclosed
US-7608563-B2 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same MITSUI AGRO CHEMICALS, INC. (JP) 2009-10-27 US disclosed
EP-1426365-B9 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME MITSUI CHEMICALS AGRO INC (JP) 2009-10-21 EP disclosed
EP-1426365-B1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME SANKYO AGRO CO LTD (JP) 2009-07-15 EP disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same CBR3, DDT, CBR1 ADRA1A 462/4885KMT2A 572/4885GLA 4026/4885
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same CBR3, DDT, CHRM2 ADRA1A 840/4885KMT2A 493/4885GLA 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.