SCHEMBL20516072

SCHEMBL20516072

O=C(O)c1ccccc1OC(F)Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.53
HSD17B10 Q99714 6/20 0.53
HPGD P15428 5/20 0.53
ALDH1A1 P00352 9/20 0.52
ESR1 P03372 1/20 0.52
ITGB3 P05106 1/20 0.52
ITGA2B P08514 1/20 0.52
HMGB1 P09429 1/20 0.52
TSHR P16473 1/20 0.52
GGT1 P19440 1/20 0.52
PTGS1 P23219 1/20 0.52
PTGS2 P35354 1/20 0.52
BLM P54132 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAPT P10636 3/20 0.50
USP2 O75604 1/20 0.50
PDE3A Q14432 1/20 0.50
KMT2A Q03164 4/20 0.49
HTT P42858 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10921765 0.87 IRAK4 (0.43) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL4299205 0.86 KDM4E (0.55) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL975946 0.86 KDM4E (0.55) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL5744926 0.83 KDM4E (0.51) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL21357575 0.83 KDM4E (0.51) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL18700962 0.83 KDM4E (0.59) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL18700983 0.83 KDM4E (0.56) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL28452350 0.81 KDM4E (0.50) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL177388 0.79 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL18700957 0.79 ALDH1A1 (0.56) KDM4EHSD17B10HPGDALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10365262-B2 Method of monitoring a parameter of a hydrocarbon well, pipeline or formation JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2019-07-30 US disclosed
US-20180284096-A1 METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION TRACERCO LIMITED (GB) 2018-10-04 US disclosed