Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28329498 | 1.00 | KDM4E (0.53) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL554352 | 0.83 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11044263 | 0.82 | ALDH1A1 (0.58) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL122686 | 0.81 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1899339 | 0.81 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL18700983 | 0.81 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL4299205 | 0.80 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28328235 | 0.80 | ALDH1A1 (0.61) | KDM4EHSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL6836605 | 0.80 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL5512458 | 0.80 | KDM4E (0.53) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |