SCHEMBL20518486

SCHEMBL20518486

O=Cc1cccc(Nc2ccccc2)c1Nc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
TDP1 Q9NUW8 5/20 0.48
MAPT P10636 5/20 0.48
KDM4E B2RXH2 3/20 0.48
GAA P10253 2/20 0.48
GLA P06280 2/20 0.48
RECQL P46063 1/20 0.48
ALDH1A1 P00352 7/20 0.44
HSD17B10 Q99714 3/20 0.44
ALOX15 P16050 3/20 0.44
TSHR P16473 3/20 0.44
CYP3A4 P08684 3/20 0.44
HPGD P15428 2/20 0.44
TP53 P04637 1/20 0.44
CDC25B P30305 1/20 0.44
ATM Q13315 1/20 0.44
LMNA P02545 3/20 0.43
BLM P54132 2/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28829584 0.84 MEN1 (0.34) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL28643879 0.84 NPC1 (0.49) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL30463062 0.84 KMT2A (0.50) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL96065 0.84 KMT2A (0.50) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL10622117 0.82 HSD17B10 (0.48) MEN1KMT2ATDP1MAPTALDH1A1
SCHEMBL28410286 0.81 MAPT (0.48) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL28969955 0.80 MAPT (0.65) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL21048723 0.79 FABP4 (0.54) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL7197542 0.77 PTGS1 (0.38) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL28685037 0.76 HSD17B10 (0.46) MEN1KMT2ATDP1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989203-B Preparation and application of D-A type BODIPY small molecular non-fullerene solar cell receptor 深圳万知达科技有限公司 2024-03-12 CN disclosed
WO-2024031993-A1 STAR-SHAPED MOLECULE CAPABLE OF BEING USED FOR HOLE TRANSPORT LAYER, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国华能集团清洁能源技术研究院有限公司 2024-02-15 WO disclosed
CN-117074380-A Method for detecting leakage of lithium battery electrolyte by using fluorescent probe molecules 中国科学院上海微系统与信息技术研究所 2023-11-17 CN disclosed
WO-2023165217-A1 1,6-DIYNE COMPOUND AND PREPARATION METHOD THEREFOR, AND PRODUCT OBTAINED USING 1,6-DIYNE COMPOUND AS RAW MATERIAL AND USE THEREOF 中国科学院福建物质结构研究所 2023-09-07 WO disclosed
CN-111548304-B Triphenylamine-based derivative, preparation method and application 百合花集团股份有限公司 2023-06-06 CN disclosed
CN-114516809-A AIE fluorescent probe based on dibenzylidene acetone and preparation method and application thereof 西华师范大学 2022-05-20 CN disclosed
CN-110117236-B Small-molecule fluorescent probe with TS as fluorophore, and preparation method and application thereof 温州医科大学 2022-03-11 CN disclosed
CN-109134379-B Triphenylamine-imidazole derivative and preparation method and application thereof 浙江工业大学 2021-05-11 CN disclosed
CN-109608402-B Imidazole derivative ionized compound and preparation method thereof 浙江工业大学 2020-10-02 CN disclosed
CN-111548304-A Derivative based on triphenylamine and preparation method and application thereof 百合花集团股份有限公司 2020-08-18 CN disclosed
CN-106674028-B Benzylidene indene dione compound, preparation thereof and application thereof in lipid drop specific imaging 华南理工大学 2020-05-22 CN disclosed
US-10577325-B2 Method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-03-03 US disclosed
US-20180282277-A1 METHOD FOR PREPARING A SERIES OF CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC LIGHT-EMITTING DIODES SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2018-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10577325-B2 Method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes CYBA, PPOX, IK MEN1 2112/4885KMT2A 3838/4885TDP1 1892/4885
US-20180282277-A1 METHOD FOR PREPARING A SERIES OF CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC LIGHT-EMITTING DIODES CYBA, PPOX, IK MEN1 2112/4885KMT2A 3838/4885TDP1 1892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.