Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463062 | 0.81 | KMT2A (0.50) | FABP4ALDH1A1HSD17B10ALOX15TP53 | |
| SCHEMBL96065 | 0.81 | KMT2A (0.50) | FABP4ALDH1A1HSD17B10ALOX15TP53 | |
| SCHEMBL20518486 | 0.79 | MEN1 (0.48) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL981676 | 0.74 | LMNA (0.55) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL28685037 | 0.74 | HSD17B10 (0.46) | FABP4ALDH1A1HSD17B10ALOX15TP53 | |
| SCHEMBL22251520 | 0.73 | ALDH1A1 (0.55) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL29458820 | 0.73 | ALDH1A1 (0.71) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL8486840 | 0.73 | MAPT (0.64) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL26538152 | 0.73 | ALDH1A1 (0.71) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL4944634 | 0.72 | THRB (0.52) | ALDH1A1HSD17B10CYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611466-B1 | SHEAR CONTROLLED RELEASE OF THROMBOLYTIC THERAPIES FOR STENOTIC LESIONS | HARVARD COLLEGE (US) | 2019-06-12 | — | — | EP | claimed |