Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946528 | 1.00 | CYP1A2 (0.61) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 | |
| SCHEMBL2221672 | 0.93 | CYP1A2 (0.59) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 | |
| Phosphonic Acid SCHEMBL27449397 | 0.90 | CYP1A2 (0.52) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 | |
| SCHEMBL347592 | 0.85 | CYP2A6 (0.80) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 | |
| SCHEMBL29407167 | 0.85 | CYP2A6 (0.80) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 | |
| Hydroquinone SCHEMBL27528335 | 0.84 | CYP1A2 (0.70) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 | |
| SCHEMBL2046459 | 0.83 | CNR1 (0.53) | CYP1A2CYP2A6ESR1ESR2CYP3A4 | |
| SCHEMBL6349150 | 0.82 | TRPA1 (0.64) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 | |
| SCHEMBL16604790 | 0.81 | ALOX5 (0.58) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL6885287 | 0.80 | CYP2A6 (0.73) | CYP1A2CYP2A6TRPA1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874153-B | Synthetic method of naphtho [2,1-d ] oxazole compound | 湖南第一师范学院 | 2023-11-17 | — | — | CN | claimed |
| CN-114874153-A | Synthetic method of naphtho [2,1-d ] oxazole compound | 湖南第一师范学院 | 2022-08-09 | — | — | CN | claimed |
| CN-110734543-A | naphthol modified phenolic resin and preparation method and application thereof | 煤炭科学技术研究院有限公司 | 2020-01-31 | — | — | CN | claimed |
| CN-1561209-A | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same | CYCLIS PHARMACEUTICALS INC (US) | 2005-01-05 | — | — | CN | claimed |
| US-20240199881-A1 | METAL COMPLEX DYES FOR INKJET PRINTING | VIDEOJET TECHNOLOGIES INC. (US) | 2024-06-20 | — | — | US | disclosed |
| EP-4381016-A1 | METAL COMPLEX DYES FOR INKJET PRINTING | Videojet Technologies Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-118043407-A | Metal complex dyes for inkjet printing | 录象射流技术公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114874153-B | Synthetic method of naphtho [2,1-d ] oxazole compound | 湖南第一师范学院 | 2023-11-17 | — | — | CN | disclosed |
| US-20230314945-A1 | NEGATIVE-TONE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-10-05 | — | — | US | disclosed |
| WO-2023014703-A1 | METAL COMPLEX DYES FOR INKJET PRINTING | VIDEOJET TECHNOLOGIES INC. (US) | 2023-02-09 | — | — | WO | disclosed |
| CN-111732508-B | Synthesis method of spiro compound | 华东师范大学 | 2022-11-01 | — | — | CN | disclosed |
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
| US-7585868-B2 | Substituted pyrazolo[3,4-D]pyrimidines as kinase antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-09-08 | — | — | US | disclosed |
| US-7514520-B2 | Process for producing phosphonitrilic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20080161513-A1 | Catalyst for Olefin Polymerization and Preparation Thereof and Polymerization Process | YINGKOU XIANGYANG CATALYST CO., LTD. (CN) | 2008-07-03 | — | — | US | disclosed |
| US-20080091050-A1 | Process For Producing Phosphonitrilic Acid Ester | ASAHI KASEI CHEMICAL CORPORATION (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20070293516-A1 | Antagonists of a lipid kinase such as a PI3 kinase, protein tyrosine kinase, and/or protein serine-threonine kinases such as mTOR; 1-isopropyl-3-(3-methoxy-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-20 | — | — | US | disclosed |
| US-20070060739-A1 | Process for producing phosphonitrilic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-03-15 | — | — | US | disclosed |
| CN-1798753-A | Process for producing phosphonitrilic acid ester | ASAHI CHEMICAL CORP (JP) | 2006-07-05 | — | — | CN | disclosed |
| CN-1561209-A | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same | CYCLIS PHARMACEUTICALS INC (US) | 2005-01-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293516-A1 | Antagonists of a lipid kinase such as a PI3 kinase, protein tyrosine kinase, and/or protein serine-threonine kinases such as mTOR; 1-isopropyl-3-(3-methoxy-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | MTOR, PI4KA, PIK3CA | CYP1A2 3815/4885CYP2A6 3435/4885TRPA1 4171/4885 |
| US-20080091050-A1 | Process For Producing Phosphonitrilic Acid Ester | PHOSPHO1, GNPAT, SELENOI | CYP1A2 1255/4885CYP2A6 929/4885TRPA1 3002/4885 |
| US-20240199881-A1 | METAL COMPLEX DYES FOR INKJET PRINTING | TP53, RB1, MDM4 | CYP1A2 235/4885CYP2A6 938/4885TRPA1 1256/4885 |
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | SERBP1, PPHLN1, VCAM1 | CYP1A2 4565/4885CYP2A6 4657/4885TRPA1 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.