SCHEMBL20520341

SCHEMBL20520341

O=C1/C(=C2\Nc3ccc(OCc4ccccc4)cc3C2=O)Nc2ccc(OCc3ccccc3)cc21

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 14/20 0.79
MAOB P27338 14/20 0.79
TOP1 P11387 1/20 0.56
GSTP1 P09211 1/20 0.51
NSD2 O96028 1/20 0.50
ABL1 P00519 1/20 0.50
PPARG P37231 1/20 0.50
RIN1 Q13671 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NCOR2 Q9Y618 1/20 0.50
CREBBP Q92793 1/20 0.50
ALOX5 P09917 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9728150 0.88 MAOB (1.00) MAOAMAOBTOP1GSTP1
SCHEMBL24701048 0.78 TOP1 (0.71) MAOAMAOBTOP1GSTP1NSD2
SCHEMBL7379163 0.77 MAOA (1.00) MAOAMAOBTOP1GSTP1NSD2
SCHEMBL27634033 0.77 MAOA (1.00) MAOAMAOBTOP1GSTP1NSD2
SCHEMBL8890233 0.76 MAOA (0.69) MAOAMAOBTOP1GSTP1CREBBP
SCHEMBL4751126 0.75 MAOB (0.78) MAOAMAOBCREBBP
SCHEMBL562544 0.75 TOP1 (0.67) MAOAMAOBTOP1GSTP1NSD2
SCHEMBL31419943 0.74 MAOB (1.00) MAOAMAOB
SCHEMBL31419937 0.74 MAOB (0.76) MAOAMAOB
SCHEMBL2236580 0.74 MAOB (1.00) MAOAMAOBCREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11196003-B2 Organic semiconductor polymers QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT (QA) 2021-12-07 US disclosed
US-20200119280-A1 ORGANIC SEMICONDUCTOR POLYMERS QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT (QA) 2020-04-16 US disclosed
US-10547005-B2 Organic semiconductor polymers QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT (QA) 2020-01-28 US disclosed
US-20180287066-A1 ORGANIC SEMICONDUCTOR POLYMERS QATAR FOUNDATION FOR EDUCATION, SCIENCE, AND COMMUNITY DEVELOPMENT (QA) 2018-10-04 US disclosed