Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 1.00 |
| ▸ | MAOA | P21397 | 13/20 | 1.00 |
| ▸ | TGM2 | P21980 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634033 | 0.88 | MAOA (1.00) | MAOBMAOATGM2TOP1GSTP1 | |
| SCHEMBL20520341 | 0.88 | MAOA (0.79) | MAOBMAOATOP1GSTP1 | |
| SCHEMBL31419937 | 0.86 | MAOB (0.76) | MAOBMAOATGM2ALDH1A1CES1 | |
| SCHEMBL31419943 | 0.86 | MAOB (1.00) | MAOBMAOATGM2ALDH1A1CES1 | |
| SCHEMBL31419946 | 0.86 | MAOB (0.76) | MAOBMAOATGM2ALDH1A1CES1 | |
| SCHEMBL31419919 | 0.85 | MAOB (0.74) | MAOBMAOATGM2ALDH1A1 | |
| SCHEMBL31419916 | 0.85 | MAOB (0.74) | MAOBMAOATGM2ALDH1A1 | |
| SCHEMBL31419914 | 0.85 | MAOB (1.00) | MAOBMAOATGM2CES1 | |
| SCHEMBL8890233 | 0.82 | MAOA (0.69) | MAOBMAOATOP1GSTP1 | |
| SCHEMBL7379163 | 0.80 | MAOA (1.00) | MAOBMAOATOP1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151518-A | N-arylation of isatins | ABBOTT LABORATORIES (US) | 1992-09-29 | — | — | US | disclosed |