SCHEMBL2052048

SCHEMBL2052048

CN1Cc2ncc(-c3ccccc3-c3csc(N(C(=O)[C@@H](CC(=O)O)CC4CCCC4)C4CC4)n3)cc2NC1=O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FFAR2 O15552 11/20 0.67
▸ SLC12A5 Q9H2X9 3/20 0.32
▸ USP19 O94966 5/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2052052 1.00 FFAR2 (0.67) FFAR2SLC12A5USP19
SCHEMBL1916275 0.90 FFAR2 (0.69) FFAR2SLC12A5USP19
SCHEMBL1916271 0.90 FFAR2 (0.69) FFAR2SLC12A5USP19
SCHEMBL1916550 0.88 FFAR2 (0.67) FFAR2SLC12A5USP19
SCHEMBL2051499 0.88 FFAR2 (0.67) FFAR2SLC12A5USP19
SCHEMBL1916544 0.88 FFAR2 (0.67) FFAR2SLC12A5USP19
SCHEMBL2051496 0.88 FFAR2 (0.67) FFAR2SLC12A5USP19
SCHEMBL2047509 0.86 FFAR2 (0.68) FFAR2SLC12A5USP19
SCHEMBL2047511 0.86 FFAR2 (0.68) FFAR2SLC12A5USP19
SCHEMBL1916978 0.85 FFAR2 (0.67) FFAR2SLC12A5USP19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110230477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2011-09-22 — — US claimed
EP-2364297-A1 Compounds, pharmaceutical composition and methods for use in treating metabolic disorders Euroscreen S.A. (BE) 2011-09-14 — — EP claimed
WO-2011076732-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING GASTROINTESTINAL DISORDERS EUROSCREEN S.A. (BE) 2011-06-30 — — WO claimed
WO-2010066682-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2010-06-17 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS CPT1A, LIPC, PC FFAR2 295/4885SLC12A5 715/4885USP19 2831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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