Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638332 | 0.75 | MEN1 (0.39) | KMT2AMEN1NOTUMSIRT2SIRT1 | |
| SCHEMBL21638335 | 0.73 | SIRT2 (0.41) | KMT2AMEN1SIRT2SIRT1GAA | |
| SCHEMBL12285262 | 0.72 | KMT2A (0.47) | KMT2AMEN1NOTUMSIRT2SIRT1 | |
| SCHEMBL25319499 | 0.71 | ALDH1A1 (0.40) | KMT2AMEN1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL21638330 | 0.71 | ALDH1A1 (0.40) | KMT2AMEN1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL6404663 | 0.67 | KMT2A (0.44) | KMT2AMEN1NOTUMSIRT2SIRT1 | |
| SCHEMBL25313673 | 0.66 | KDM1A (0.36) | SIRT2SIRT1AADATTSHR | |
| SCHEMBL22769484 | 0.66 | MEN1 (0.38) | KMT2AMEN1SIRT2SIRT1AADAT | |
| SCHEMBL892631 | 0.65 | NOTUM (0.51) | KMT2AMEN1NOTUMGAAFPR2 | |
| SCHEMBL25315680 | 0.65 | SIRT2 (0.38) | KMT2ANOTUMSIRT2SIRT1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018178014-A1 | 4-CYCLOPROPYL-2-OXOPYRROLIDINE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HERBICIDAL PLANT PROTECTION AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-04 | — | — | WO | disclosed |