SCHEMBL22769484

SCHEMBL22769484

NC(=O)C1C(=O)N(c2cccc(F)c2F)CC1Cc1ccc(F)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPT P10636 2/20 0.36
GLA P06280 1/20 0.36
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
LMNA P02545 1/20 0.35
AADAT Q8N5Z0 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KCNQ2 O43526 1/20 0.32
HTT P42858 1/20 0.32
AMPD2 Q01433 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28199040 0.76 MEN1 (0.36) MEN1KMT2APOLB
SCHEMBL25313673 0.73 KDM1A (0.36) AADATSIRT2SIRT1
SCHEMBL28199669 0.72 BPTF (0.40) MEN1KMT2AMAPTHTT
SCHEMBL25315680 0.71 SIRT2 (0.38) KMT2AMAPTAADATSIRT2SIRT1
SCHEMBL25318566 0.71 REN (0.35) MAPTAADATKDM4ETDP1HTT
SCHEMBL25317840 0.70 HTR2B (0.38) MEN1KMT2ALMNASIRT2SIRT1
SCHEMBL25315349 0.68 HRH3 (0.37)
SCHEMBL20520940 0.66 KMT2A (0.43) MEN1KMT2AMAPTLMNAAADAT
SCHEMBL22493133 0.65 FPR2 (0.39)
SCHEMBL22493139 0.65 FPR2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3303287-B1 SUBSTITUTED CYCLIC AMIDES AS HERBICIDES FMC CORP (US) 2020-12-16 EP claimed