SCHEMBL2052136

SCHEMBL2052136

Cc1ccc(S(=O)(=O)Oc2cc(Cl)nnc2Oc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.53
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
MCOLN3 Q8TDD5 1/20 0.53
KDM4E B2RXH2 2/20 0.45
P2RY1 P47900 5/20 0.44
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
FFAR1 O14842 1/20 0.41
CDK1 P06493 1/20 0.41
CCNB1 P14635 1/20 0.41
CCNA2 P20248 1/20 0.41
CDK2 P24941 1/20 0.41
CDK7 P50613 1/20 0.41
CCNH P51946 1/20 0.41
CCNA1 P78396 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
ADORA2A P29274 1/20 0.39
TEAD1 P28347 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2047482 0.91 ALDH1A1 (0.42) NPSR1ALDH1A1MEN1KMT2AMCOLN3
SCHEMBL2050066 0.86 KMT2A (0.43) NPSR1ALDH1A1MEN1KMT2AMCOLN3
SCHEMBL2050291 0.85 POLB (0.40) NPSR1ALDH1A1MEN1KMT2AMCOLN3
SCHEMBL2049389 0.82 P2RY2 (0.45) MEN1KMT2AL3MBTL1
SCHEMBL2047804 0.80 LMNA (0.45) NPSR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL2050269 0.79 KMT2A (0.41) NPSR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL2236222 0.78 MEN1 (0.55) NPSR1ALDH1A1MEN1KMT2AMCOLN3
SCHEMBL29599829 0.78 MEN1 (0.55) NPSR1ALDH1A1MEN1KMT2AMCOLN3
SCHEMBL2049794 0.78 LMNA (0.43) NPSR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL2052229 0.77 ALDH1A1 (0.43) NPSR1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964531-B2 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2011-06-21 US disclosed
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2010-02-18 US disclosed
US-7608563-B2 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same MITSUI AGRO CHEMICALS, INC. (JP) 2009-10-27 US disclosed
EP-1426365-B9 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME MITSUI CHEMICALS AGRO INC (JP) 2009-10-21 EP disclosed
EP-1426365-B1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME SANKYO AGRO CO LTD (JP) 2009-07-15 EP disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same CBR3, DDT, CBR1 NPSR1 2143/4885ALDH1A1 447/4885MEN1 4596/4885
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same CBR3, DDT, CHRM2 NPSR1 2101/4885ALDH1A1 762/4885MEN1 4495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.