SCHEMBL20522291

SCHEMBL20522291

COc1ccc(-c2c(C)cccc2NCc2ccc3[nH]cnc3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
QPCTL Q9NXS2 2/20 0.42
ACP1 P24666 4/20 0.41
QPCT Q16769 4/20 0.40
NCF1 P14598 1/20 0.40
MMP12 P39900 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
EGFR P00533 1/20 0.39
IGF1R P08069 1/20 0.39
KDR P35968 1/20 0.39
BRD4 O60885 1/20 0.38
CD38 P28907 1/20 0.38
BACE1 P56817 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29550849 1.00 QPCTL (0.42) QPCTLACP1QPCTNCF1MMP12
SCHEMBL29550917 0.88 QPCT (0.51) QPCTLQPCTMEN1KMT2AGAA
SCHEMBL20522388 0.88 QPCT (0.51) QPCTLQPCTMEN1KMT2AGAA
SCHEMBL22712388 0.84 ACP1 (0.46) QPCTLACP1QPCTNCF1MMP12
SCHEMBL29550590 0.84 ACP1 (0.46) QPCTLACP1QPCTNCF1MMP12
SCHEMBL20522328 0.82 KDR (0.45) QPCTLACP1QPCTMMP12KDR
SCHEMBL29551454 0.82 KDR (0.45) QPCTLACP1QPCTMMP12KDR
SCHEMBL20522378 0.78 QPCT (0.40) QPCTLACP1QPCTMMP12
SCHEMBL20522302 0.78 SLC22A12 (0.42) QPCTLACP1QPCTMMP12EGFR
SCHEMBL29550661 0.78 QPCT (0.40) QPCTLACP1QPCTMMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110719910-B Novel inhibitors 维沃里翁治疗股份有限公司 2023-07-21 CN claimed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US claimed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US claimed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP claimed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO claimed
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 US disclosed
CN-117024352-A Novel inhibitors 维沃里翁治疗股份有限公司 2023-11-10 CN disclosed
CN-110719910-B Novel inhibitors 维沃里翁治疗股份有限公司 2023-07-21 CN disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP disclosed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 QPCTL 60/4885ACP1 900/4885QPCT 6/4885
US-20200377493-A1 NOVEL INHIBITORS GLUL, GLS, QPCT QPCTL 7/4885ACP1 835/4885QPCT 3/4885
US-11339152-B2 Inhibitors GLUL, QPCT, GLS QPCTL 7/4885ACP1 913/4885QPCT 2/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 QPCTL 8/4885ACP1 1264/4885QPCT 2/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT QPCTL 8/4885ACP1 552/4885QPCT 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.