Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30610420 | 1.00 | CYP3A4 (0.46) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL30234670 | 0.89 | CYP3A4 (0.43) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3784827 | 0.87 | TAAR1 (0.45) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3793176 | 0.84 | CYP3A4 (0.45) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL13615034 | 0.84 | TTR (0.56) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL4910768 | 0.83 | ADORA2A (0.41) | CYP3A4CYP1A2CYP2C19TTRL3MBTL1 | |
| SCHEMBL20522406 | 0.83 | CYP1A2 (0.49) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9681067 | 0.81 | CD44 (0.46) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL2934681 | 0.79 | TSHR (0.43) | CYP3A4ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL2498725 | 0.79 | ALOX5AP (0.44) | CYP3A4CYP1A2CYP2C19CYP2C9TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001873-A1 | NOVEL INHIBITORS | VIVORYON THERAPEUTICS N.V. (DE) | 2026-01-01 | — | — | US | disclosed |
| US-12384772-B2 | Inhibitors | VIVORYON THERAPEUTICS N.V. (DE) | 2025-08-12 | — | — | US | disclosed |
| US-20220274977-A1 | NOVEL INHIBITORS | VIVORYON THERAPEUTICS N.V. (DE) | 2022-09-01 | — | — | US | disclosed |
| US-11339152-B2 | Inhibitors | VIVORYON THERAPEUTICS N.V. | 2022-05-24 | — | — | US | disclosed |
| US-20200377493-A1 | NOVEL INHIBITORS | VIVORYON THERAPEUTICS N.V. (DE) | 2020-12-03 | — | — | US | disclosed |
| EP-3601269-A1 | NOVEL INHIBITORS | Probiodrug AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018178384-A1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2018-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001873-A1 | NOVEL INHIBITORS | GLS, GLS2, SULT1E1 | CYP3A4 632/4885ALDH1A1 1183/4885CYP1A2 839/4885 |
| US-20200377493-A1 | NOVEL INHIBITORS | GLUL, GLS, QPCT | CYP3A4 987/4885ALDH1A1 1681/4885CYP1A2 723/4885 |
| US-11339152-B2 | Inhibitors | GLUL, QPCT, GLS | CYP3A4 1145/4885ALDH1A1 1490/4885CYP1A2 714/4885 |
| US-12384772-B2 | Inhibitors | GLS, QPCT, GLS2 | CYP3A4 1109/4885ALDH1A1 1415/4885CYP1A2 744/4885 |
| US-20220274977-A1 | NOVEL INHIBITORS | GLUL, GLS, QPCT | CYP3A4 953/4885ALDH1A1 1184/4885CYP1A2 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.