Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30507348 | 0.87 | MGAM (0.46) | CYP3A4MGAMGAASIMGAM2 | |
| SCHEMBL25011940 | 0.87 | CD44 (0.54) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL30234670 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL3789888 | 0.83 | CD44 (0.50) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL9681003 | 0.83 | CD44 (0.50) | CD44CYP3A4TDP1GAATSHR | |
| SCHEMBL20522391 | 0.81 | CYP3A4 (0.46) | CYP3A4TDP1QPCTTSHRALDH1A1 | |
| SCHEMBL3793739 | 0.80 | CYP3A4 (0.54) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL9680722 | 0.79 | SENP1 (0.48) | CD44CYP3A4TDP1MGAMGAA | |
| Hydrochloric Acid SCHEMBL9312867 | 0.78 | CYP3A4 (0.58) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL2934681 | 0.78 | TSHR (0.43) | CYP3A4TDP1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |