Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961559 | 0.82 | TP53 (0.57) | HTTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL57554 | 0.77 | SMN1; SMN2 (0.70) | HTTLMNAALDH1A1KDM4EKMT2A | |
| Benzene SCHEMBL28977956 | 0.77 | SMN1; SMN2 (0.70) | HTTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL9872789 | 0.74 | HTT (0.45) | HTTLMNAALDH1A1KDM4ETP53 | |
| SCHEMBL27966285 | 0.73 | ALDH1A1 (0.46) | HTTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL4051171 | 0.73 | RAB9A (0.69) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL9282775 | 0.73 | HTT (1.00) | HTTLMNAALDH1A1KMT2ATP53 | |
| N-Piperidinobenzamide SCHEMBL696161 | 0.73 | HTT (1.00) | HTTLMNAALDH1A1KMT2ATP53 | |
| SCHEMBL420582 | 0.73 | RAB9A (0.69) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| Hydrazine SCHEMBL28432690 | 0.72 | SMN1; SMN2 (0.64) | HTTLMNAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130108653-A1 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | AARHUS UNIVERSITET (DK) | 2013-05-02 | — | — | US | claimed |
| EP-2516459-A1 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | Aarhus Universitet (University Of Aarhus) (DK) | 2012-10-31 | — | — | EP | claimed |
| WO-2011077093-A1 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | AARHUS UNIVERSITET (DK) | 2011-06-30 | — | — | WO | claimed |
| US-20130108653-A1 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | AARHUS UNIVERSITET (DK) | 2013-05-02 | — | — | US | disclosed |
| EP-2516459-A1 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | Aarhus Universitet (University Of Aarhus) (DK) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077093-A1 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | AARHUS UNIVERSITET (DK) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130108653-A1 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | CD4, HAVCR2, BST2 | HTT 4781/4885LMNA 2822/4885ALDH1A1 3644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.