SCHEMBL20524652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2745323	0.81	TDP1 (0.51)	TDP1POLBHPGDGABRPGABRD
	SCHEMBL1018930	0.81	ALDH1A1 (0.41)	TDP1POLBHPGDGABRPGABRD
	SCHEMBL9622627	0.80	POLB (0.50)	TDP1POLBHPGDGABRPGABRD
	SCHEMBL3444671	0.79	MEN1 (0.50)	TDP1POLBKDM4EKMT2AMEN1
	SCHEMBL10827865	0.77	POLB (0.47)	TDP1POLBHPGDGABRPGABRD
	SCHEMBL10827596	0.77	HPGD (0.63)	TDP1POLBHPGDGABRPGABRD
	SCHEMBL1434641	0.76	HPGD (0.61)	TDP1POLBHPGDGABRPGABRD
	SCHEMBL21384234	0.76	TDP1 (0.46)	TDP1POLBHPGDGABRPGABRD
	SCHEMBL22868013	0.76	POLB (0.46)	TDP1POLBHPGDKDM4EKMT2A
	SCHEMBL1013091	0.76	MAOB (0.37)	HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.