Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 3/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 16/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525806 | 0.99 | QPCT (0.39) | AXLQPCTMET | |
| SCHEMBL371695 | 0.87 | AXL (0.48) | AXLMET | |
| SCHEMBL372044 | 0.86 | EHMT2 (0.47) | AXLQPCTMET | |
| SCHEMBL24444554 | 0.83 | MET (0.43) | AXLMET | |
| SCHEMBL20525710 | 0.83 | KCNA3 (0.39) | QPCTMET | |
| SCHEMBL20525526 | 0.79 | RIPK1 (0.41) | — | |
| SCHEMBL20525747 | 0.77 | KDM4E (0.44) | — | |
| SCHEMBL20525612 | 0.77 | ILK (0.38) | — | |
| SCHEMBL20525797 | 0.75 | MET (0.58) | AXLMET | |
| SCHEMBL24444355 | 0.75 | FGFR2 (0.41) | AXLQPCTMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101759-B1 | METHODS OF USING MEK INHIBITORS | EXELIXIS INC (US) | 2018-10-10 | — | — | EP | claimed |