Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235861 | 0.92 | SMN1; SMN2 (0.51) | SIGMAR1ALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL1516416 | 0.90 | TAAR1 (0.47) | SIGMAR1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL29787841 | 0.90 | IDO1 (0.50) | SIGMAR1ALDH1A1KCNH2TMEM97SMN1; SMN2 | |
| SCHEMBL24801993 | 0.89 | SIGMAR1 (0.68) | SIGMAR1BCHESMN1; SMN2KDM4E | |
| SCHEMBL3112736 | 0.89 | SIGMAR1 (0.68) | SIGMAR1BCHESMN1; SMN2KDM4E | |
| SCHEMBL29787770 | 0.87 | ALDH1A1 (0.50) | SIGMAR1ALDH1A1KCNH2TMEM97MEN1 | |
| SCHEMBL20502219 | 0.87 | L3MBTL1 (0.56) | ALDH1A1SMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL29501164 | 0.87 | ALDH1A1 (0.45) | SIGMAR1ALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL17509724 | 0.85 | MEN1 (0.44) | SIGMAR1ALDH1A1KCNH2TMEM97BCHE | |
| SCHEMBL12954738 | 0.85 | ALDH1A1 (0.71) | SIGMAR1ALDH1A1KCNH2TMEM97MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180382-B1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | SIKA TECH AG (CH) | 2018-10-10 | — | — | EP | claimed |
| EP-3180382-B1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | SIKA TECH AG (CH) | 2018-10-10 | — | — | EP | disclosed |