Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525820 | 0.90 | MET (0.51) | METKDRIGF1R | |
| SCHEMBL20525707 | 0.89 | MET (0.49) | METKDROPRD1IGF1R | |
| SCHEMBL371808 | 0.88 | MET (0.67) | METKDRAXL | |
| SCHEMBL20525633 | 0.85 | MET (0.52) | METKDRAXL | |
| SCHEMBL20525675 | 0.84 | POLB (0.58) | METKDRAXL | |
| SCHEMBL20525748 | 0.83 | MET (0.49) | METKDRIGF1R | |
| SCHEMBL20525668 | 0.80 | MET (0.52) | METKDRIGF1R | |
| SCHEMBL20525731 | 0.80 | MET (0.49) | METKDRAXL | |
| SCHEMBL29693638 | 0.79 | MET (0.63) | METKDR | |
| SCHEMBL371714 | 0.79 | MET (0.63) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101759-B1 | METHODS OF USING MEK INHIBITORS | EXELIXIS INC (US) | 2018-10-10 | — | — | EP | claimed |