Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525580 | 0.90 | MET (0.51) | METKDRIGF1R | |
| SCHEMBL20525679 | 0.88 | MET (0.51) | METKDRIGF1R | |
| SCHEMBL20525537 | 0.87 | MET (0.52) | METKDRIGF1R | |
| SCHEMBL371708 | 0.87 | MET (0.68) | METKDR | |
| SCHEMBL20525633 | 0.87 | MET (0.52) | METKDR | |
| SCHEMBL20525675 | 0.86 | POLB (0.58) | METKDR | |
| SCHEMBL20525748 | 0.85 | MET (0.49) | METKDRIGF1R | |
| SCHEMBL20525668 | 0.82 | MET (0.52) | METKDRIGF1R | |
| SCHEMBL20525731 | 0.80 | MET (0.49) | METKDR | |
| SCHEMBL20525545 | 0.80 | MET (0.53) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101759-B1 | METHODS OF USING MEK INHIBITORS | EXELIXIS INC (US) | 2018-10-10 | — | — | EP | claimed |