Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HGF | P14210 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525564 | 0.90 | MET (0.34) | METMEN1KMT2A | |
| SCHEMBL371933 | 0.89 | MET (0.48) | METHGFMST1RAXL | |
| SCHEMBL15404759 | 0.80 | MET (0.43) | METHGFMST1R | |
| SCHEMBL377067 | 0.79 | MET (0.48) | METAXL | |
| SCHEMBL20525677 | 0.77 | MET (0.46) | METHGFMST1R | |
| SCHEMBL20525830 | 0.74 | MET (0.52) | MET | |
| SCHEMBL15404611 | 0.73 | CYP3A4 (0.46) | METMEN1KMT2AHGFMST1R | |
| SCHEMBL15405168 | 0.73 | MET (0.41) | MET | |
| SCHEMBL17880565 | 0.73 | MET (0.51) | METHGFMST1RAXL | |
| SCHEMBL15404589 | 0.72 | MET (0.38) | METHGFMST1RAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101759-B1 | METHODS OF USING MEK INHIBITORS | EXELIXIS INC (US) | 2018-10-10 | — | — | EP | claimed |