SCHEMBL20526412

SCHEMBL20526412

[Pt].[c]1ccc(-c2cccc3c2Cc2ccccc2O3)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
MAPKAPK2 P49137 1/20 0.39
PRCP P42785 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ANPEP P15144 2/20 0.31
IL1RN P18510 1/20 0.31
ERAP2 Q6P179 1/20 0.31
ERAP1 Q9NZ08 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
PNMT P11086 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15391341 0.98 MAOA (0.48) MAOAMAOBMAPKAPK2PRCPGAA
SCHEMBL30859067 0.85 MAOA (0.55) MAOAMAOBMAPKAPK2PRCPANPEP
SCHEMBL149766 0.85 MAOA (0.55) MAOAMAOBMAPKAPK2PRCPANPEP
Hydrochloric Acid SCHEMBL28967142 0.84 MAOA (0.53) MAOAMAOBMAPKAPK2PRCPANPEP
SCHEMBL27773304 0.80 MAOB (0.48) MAOAMAOBMAPKAPK2PNMT
SCHEMBL28252708 0.80 MAOB (0.48) MAOAMAOBMAPKAPK2PRCPGAA
SCHEMBL28299306 0.80 MAOA (0.48) MAOAMAOBMAPKAPK2PRCPGAA
SCHEMBL550237 0.77 PNMT (0.47) MAOAPRCPANPEPIL1RNERAP2
SCHEMBL28425586 0.77 ANPEP (0.39) MAOAPRCPANPEPIL1RNERAP2
SCHEMBL11572806 0.77 MAOB (0.44) MAOAMAOBMAPKAPK2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103732374-B Irradiation and shaping unit 迈图高新材料股份有限公司 2018-10-30 CN disclosed
EP-3383954-A1 PHOTOACTIVATABLE MULTI-COMPONENT SYSTEMS FOR PRODUCING A FOAMED SILICONE COMPOSITION Sonderhoff Chemicals GmbH (DE) 2018-10-10 EP disclosed
CN-102933366-A Integrated irradiation device MOMENTIVE PERFORMANCE MAT INC 2013-02-13 CN disclosed
CN-102015845-A Process for the continuous manufacturing of shaped articles and use of silicone rubber compositions in that process MOMENTIVE PERFORMANCE MAT INC 2011-04-13 CN disclosed