Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20526848 | 1.00 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL20526851 | 1.00 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL16459874 | 0.90 | MAOA (0.49) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL16459872 | 0.90 | MAOA (0.49) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL28379320 | 0.85 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL16471827 | 0.85 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL7620931 | 0.82 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL2562282 | 0.82 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL2558333 | 0.82 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL9914144 | 0.82 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377732-B2 | Process for preparing aminotetrahydropyrans | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2019-08-13 | — | — | US | disclosed |
| US-20180290995-A1 | Process For Preparing Aminotetrahydropyrans | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2018-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377732-B2 | Process for preparing aminotetrahydropyrans | DPP4, DPP3, DPP9 | MAOA 652/4885NR4A1 2943/4885USP2 1308/4885 |
| US-20180290995-A1 | Process For Preparing Aminotetrahydropyrans | DPP4, DPP3, DPP9 | MAOA 652/4885NR4A1 2943/4885USP2 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.