Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16459874 | 1.00 | MAOA (0.49) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL20526848 | 0.90 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL20526850 | 0.90 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL20526851 | 0.90 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL7620931 | 0.83 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL2562282 | 0.83 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL9914144 | 0.83 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL2558333 | 0.83 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL6823748 | 0.83 | MAOA (0.51) | MAOANR4A1USP2MEN1NPC1 | |
| SCHEMBL28379320 | 0.80 | MAOA (0.55) | MAOANR4A1USP2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-9290591-B2 | Iron complexes and methods for polymerization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-22 | — | — | US | disclosed |
| US-9290591-B2 | Iron complexes and methods for polymerization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-22 | — | — | US | disclosed |
| US-9290591-B2 | Iron complexes and methods for polymerization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140011971-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |
| US-20140011971-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |
| US-20140011971-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | FTH1, TFRC, FDPS | MAOA 1692/4885NR4A1 3251/4885USP2 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.